🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Writer Login
Latest
Priya Life Science Sponsor trial record
Trackers Companies Trial finder
Sponsor · clinical trials

Merus clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our USA and UK registers with Merus as lead sponsor. Synced 26 Sep 2026
4Current trials
1Recruiting now
4Drugs in these trials
2Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Merus is the lead sponsor of 4 current clinical trials in our USA and UK registers. 1 is recruiting patients now. The most common phase is Phase 1/2. The drugs named most often in its trials are Petosemtamab, MCLA-129 and Osimertinib. The most-studied condition is Head and Neck Squamous Cell Carcinoma.

ClinicalTrials.gov trials by status

  • Recruiting125%
  • Active, closed375%

Trials by phase

  • Phase 1/2250%
  • Phase 3250%
01

Clinical trials sponsored by Merus

4 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
NCT03526835 · ClinicalTrials.gov ↗ · Advanced/Metastatic Solid Tumors, Colorectal Cancer, Gastric Cancer
Phase 1/2 Recruiting 2018-05 UK, USA
Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination
NCT04868877 · Non-Small Cell Lung Cancer Metastatic, Gastric Cancer, Esophageal Squamous Cell Carcinoma
Phase 1/2 Active, closed 2021-04 USA
A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)
NCT06496178 · ClinicalTrials.gov ↗ · Head and Neck Squamous Cell Carcinoma
Phase 3 Active, closed 2024-06 UK, USA
A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)
NCT06525220 · ClinicalTrials.gov ↗ · Head and Neck Squamous Cell Carcinoma
Phase 3 Active, closed 2024-09 UK, USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Drugs in Merus trials

4 compounds

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

03

Conditions in Merus trials

7 conditions
04

By trial register

RegisterTrialsRecruiting
Clinical trials in USA41
Clinical trials in UK31

A trial with sites in more than one country appears in each of those registers.

05

Other sponsors in Head and Neck Squamous Cell Carcinoma

SponsorTrials
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University7
West China Hospital6
Beijing Tongren Hospital3
ALX Oncology2
Fifth Affiliated Hospital, Sun Yat-Sen University2
Bicara Therapeutics1
Rajiv Gandhi Cancer Institute & Research Center, India1
CSPC Megalith Biopharmaceutical1
Man Hu1

Sponsors with the most current trials registered for this condition.

06

Questions about Merus trials

How many clinical trials does Merus sponsor?

Merus is the lead sponsor of 4 current trials on ClinicalTrials.gov in our USA and UK registers, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Merus trials recruiting?

Yes. 1 of its 4 ClinicalTrials.gov trials is recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Merus testing?

Its current trials name 4 drugs and biologicals as interventions. The most frequent are Petosemtamab (2), MCLA-129 (1), Osimertinib (1) and Pembrolizumab (1). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

Approvals, shortages and trials, every Friday

One email a week with new EMA and FDA approvals, EU and US medicine shortages, how many trials are recruiting in Ireland, and the week's Irish pharma news.

Free. Unsubscribe from any email with one click. See our privacy policy.

How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.