Cybin IRL is the lead sponsor of 3 current clinical trials in our USA, UK and Ireland registers. 1 is recruiting patients now. All registered phases are Phase 3. The drugs named most often in its trials are CYB003. The most-studied condition is Major Depressive Disorder.
| Study | Phase | Status | Start | Registers |
|---|---|---|---|---|
|
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
NCT06793397 · ClinicalTrials.gov ↗ · Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder
Drug: CYB003 |
Phase 3 | Recruiting | 2025-12 | Ireland, UK, USA |
|
Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)
NCT06605105 · ClinicalTrials.gov ↗ · Major Depressive Disorder
Drug: CYB003 |
Phase 3 | By invitation | 2025-07 | UK, USA |
|
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"
NCT06564818 · ClinicalTrials.gov ↗ · Major Depressive Disorder
Drug: CYB003 |
Phase 3 | Active, closed | 2024-12 | USA |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.
Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 3 | 1 |
| Clinical trials in UK | 2 | 1 |
| Clinical trials in Ireland | 1 | 1 |
A trial with sites in more than one country appears in each of those registers.
| Sponsor | Trials |
|---|---|
| Neurocrine Biosciences | 6 |
| Xenon Pharmaceuticals | 3 |
| Definium Therapeutics US | 2 |
| Syndeio Biosciences | 2 |
| Alto Neuroscience | 1 |
| Shandong Provincial Hospital | 1 |
Sponsors with the most current trials registered for this condition.
Cybin IRL is the lead sponsor of 3 current trials on ClinicalTrials.gov in our USA, UK and Ireland registers, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.
Yes. 1 of its 3 ClinicalTrials.gov trials is recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Its current trials name 1 drug or biological as interventions. The most frequent are CYB003 (3). The number in brackets is how many of its trials name each drug.
Yes. 1 trial in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.
Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.
Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.