Ifinatamab Deruxtecan is named as an intervention in 17 current clinical trials in our USA, China, UK and Ireland registers. 15 are recruiting patients now. The most common phase is Phase 1/2. The sponsor with the most trials is Merck Sharp & Dohme LLC (10). The most-studied condition is Small Cell Lung Cancer.
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Condition (as registered) | Trials |
|---|---|
| Small Cell Lung Cancer | 2 |
| Esophageal Squamous Cell Carcinoma | 2 |
| Carcinoma, Non-Small-Cell Lung | 2 |
| Prostate Cancer | 1 |
| Prostatic Neoplasms | 1 |
| Castration-Resistant Prostatic Cancer | 1 |
| Metastasis | 1 |
| Recurrent or Metastatic Solid Tumors | 1 |
| Malignant Neoplasm | 1 |
| Extensive-stage Small-cell Lung Cancer | 1 |
| Small-Cell Lung Cancer | 1 |
| Neuroendocrine Carcinoma | 1 |
| Advanced Solid Tumor | 1 |
| Malignant Solid Tumor | 1 |
| Extensive Stage-small Cell Lung Cancer | 1 |
| Small Cell Lung Cancer Extensive Stage | 1 |
| Oesophageal Squamous Cell Carcinoma | 1 |
| Lung Neoplasm | 1 |
| Lead sponsor | Trials |
|---|---|
| Merck Sharp & Dohme LLC | 10 |
| Daiichi Sankyo | 6 |
| Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 1 |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 17 | 15 |
| Clinical trials in China | 10 | 9 |
| Clinical trials in UK | 4 | 4 |
| Clinical trials in Ireland | 3 | 3 |
A trial with sites in more than one country appears in each of those registers.
17 current trials in our USA, China, UK and Ireland registers name Ifinatamab Deruxtecan (also registered as DS-7300a) as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.
Yes. 15 of the 17 trials are recruiting: 15 with sites in USA, 9 with sites in China, 4 with sites in UK and 3 with sites in Ireland. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Merck Sharp & Dohme LLC (10), Daiichi Sankyo (6) and Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1). The number in brackets is how many trials each organisation leads.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Ifinatamab Deruxtecan works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Ifinatamab Deruxtecan works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Ifinatamab Deruxtecan (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.