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Compound · clinical trials

Bupivacaine hydrochloride clinical trials

Also listed in trial records as Marcaine, Sensorcaine
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 12 trials in our China register that name Bupivacaine hydrochloride as an intervention. Synced 25 Sep 2026
12Current trials
10Recruiting now
7Lead sponsors
1Country register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Bupivacaine hydrochloride is named as an intervention in 12 current clinical trials in our China register. 10 are recruiting patients now. The most common phase is Not applicable. The sponsor with the most trials is Beijing Tiantan Hospital (6). The most-studied condition is Liposomal Bupivacaine.

Trials by status

  • Recruiting1083%
  • Not yet open18%
  • By invitation18%

Trials by phase

  • Not applicable975%
  • Phase 4217%
  • Phase 218%
01

Clinical trials of Bupivacaine hydrochloride

12 trials
StudyPhaseStatusLead sponsorRegisters
Efficacy and Safety of Liposomal Bupivacaine Injection for Paravertebral Nerve Block in the Treatment of Acute and Chronic Pain After Thoracoscopic Pneumonectomy: A Multicenter, Randomized, Double-blind, Controlled Clinical Trial
NCT06569953 · ClinicalTrials.gov ↗ · Acute Pain, Chronic Pain, Postoperative Pain
Phase 4 Recruiting The Second Affiliated Hospital of Chongqing Medical University China
Effect of Intercostal Nerve Block With Liposomal Bupivacaine on Quality of Recovery in VATS Partial Pneumonectomy
NCT07512635 · ClinicalTrials.gov ↗ · Pulmonary Nodule, Liposomal Bupivacaine
Phase 4 Recruiting Sanming First Hospital China
A Study of Bupivacaine Liposome Injection in the Treatment of Pain After Thoracoscopic Surgery
NCT06529432 · ClinicalTrials.gov ↗ · Local Analgesia Via Nerve Block
Phase 2 Recruiting Jiangsu HengRui Medicine Co., Ltd. China
Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery
NCT06704698 · ClinicalTrials.gov ↗ · Pain Syndrome, Dizziness, Vomiting
Not applicable Recruiting Zhejiang Cancer Hospital China
The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Video-assisted Thoracoscopic Surgery
NCT07432711 · Video-assisted Thoracoscopic Surgery (VATS), Pain Management, Liposomal Bupivacaine
Not applicable Recruiting Beijing Tiantan Hospital China
The Efficacy and Safety of Liposomal Bupivacaine for Rhomboid Intercostal Nerve Block in Relieving Postoperative Pain After Video-assisted Thoracoscopic Surgery
NCT07441902 · ClinicalTrials.gov ↗ · Video-assisted Thoracoscopic Surgery (VATS), Pain Management, Liposomal Bupivacaine
Not applicable Recruiting Beijing Tiantan Hospital China
The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Hemorrhoid Surgery
NCT07442539 · ClinicalTrials.gov ↗ · Hemorrhoid Surgery, Liposome Bupivacaine, Pain Management
Not applicable Recruiting Beijing Tiantan Hospital China
The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Laparoscopic Surgery
NCT07458256 · ClinicalTrials.gov ↗ · Laparoscopic Surgery, Liposomal Bupivacaine, Local Infiltration
Not applicable Recruiting Beijing Tiantan Hospital China
The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery
NCT07458282 · ClinicalTrials.gov ↗ · Laparoscopic Surgery, Liposomal Bupivacaine, Transversus Abdominis Plane Block
Not applicable Recruiting Beijing Tiantan Hospital China
The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic Oncology
NCT07458295 · ClinicalTrials.gov ↗ · Laparoscopic Surgery, Gynecologic Oncology Patient, Liposomal Bupivacaine
Not applicable Recruiting Beijing Tiantan Hospital China
The Effect of Liposomal Bupivacaine Erector Spinae Plane Block
NCT07667439 · ClinicalTrials.gov ↗ · Liposome Bupivacaine, Erector Spinae Plane Block, Postoperative Analgesia
Not applicable Not yet open Second Affiliated Hospital, Zhejiang University, School of Medicine China
Effect of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Superior Trunk Block of the Interscalene Brachial Plexus on Postoperative Diaphragmatic Function and Analgesia
NCT07587203 · ClinicalTrials.gov ↗ · Proximal Humerus Surgery, Rotator Cuff Surgery, Shoulder Arthroplasty
Not applicable By invitation Nanjing First Hospital, Nanjing Medical University China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Bupivacaine hydrochloride across our data

Ireland · EU · US

The same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.

Licensed in Ireland (HPRA)

7 single-substance products containing Bupivacaine hydrochloride on the HPRA medicines list.

All 7 Irish products →

Supply shortages

  • Bupivacaine Hydrochloride, Epinephrine Bitartrate InjectionUS (FDA) · Current · updated 22 Sep 2026
  • Bupivacaine Hydrochloride InjectionUS (FDA) · Current · updated 22 Sep 2026
03

Conditions studied with Bupivacaine hydrochloride

27 conditions
Liposomal Bupivacaine6Pain Management3Laparoscopic Surgery3Video-assisted Thoracoscopic Surgery (VATS)2Liposome Bupivacaine2Local Infiltration2Transversus Abdominis Plane Block2Local Injection1Acute Pain1Chronic Pain1Postoperative Pain1Pulmonary Nodule1
All 27 conditions
Condition (as registered)Trials
Liposomal Bupivacaine6
Pain Management3
Laparoscopic Surgery3
Video-assisted Thoracoscopic Surgery (VATS)2
Liposome Bupivacaine2
Local Infiltration2
Transversus Abdominis Plane Block2
Local Injection1
Acute Pain1
Chronic Pain1
Postoperative Pain1
Pulmonary Nodule1
Pain Syndrome1
Dizziness1
Vomiting1
Itching1
Local Analgesia Via Nerve Block1
Hemorrhoid Surgery1
Proximal Humerus Surgery1
Rotator Cuff Surgery1
Shoulder Arthroplasty1
Shoulder Arthroscopy1
Erector Spinae Plane Block1
Postoperative Analgesia1
Randomized Controlled Trial1
Rhomboid Intercostal Block1
Gynecologic Oncology Patient1
04

Sponsors

lead sponsor per trial
Lead sponsorTrials
Beijing Tiantan Hospital6
The Second Affiliated Hospital of Chongqing Medical University1
Sanming First Hospital1
Zhejiang Cancer Hospital1
Jiangsu HengRui Medicine Co., Ltd.1
Nanjing First Hospital, Nanjing Medical University1
Second Affiliated Hospital, Zhejiang University, School of Medicine1
05

By country register

RegisterTrialsRecruiting
Clinical trials in China1210

A trial with sites in more than one country appears in each of those registers.

06

Related compounds

07

Questions about Bupivacaine hydrochloride trials

How many clinical trials are testing Bupivacaine hydrochloride?

12 current trials in our China register name Bupivacaine hydrochloride as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Bupivacaine hydrochloride trials recruiting patients?

Yes. 10 of the 12 trials are recruiting: 10 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Bupivacaine hydrochloride clinical trials?

Beijing Tiantan Hospital (6), The Second Affiliated Hospital of Chongqing Medical University (1), Sanming First Hospital (1) and Zhejiang Cancer Hospital (1), among 7 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Is Bupivacaine hydrochloride licensed in Ireland?

Yes. The HPRA medicines list includes 7 single-substance products containing Bupivacaine hydrochloride, for example Bupivacaine Heavy 5 mg/ml solution for injection (Laboratoire Aguettant). A licence does not mean a product is currently marketed or reimbursed; see each product's record.

Is there a Bupivacaine hydrochloride shortage?

The registers we track list 2 entries for Bupivacaine hydrochloride: US FDA: current; US FDA: current. Shortages are product- and country-specific; check with a pharmacist.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Bupivacaine hydrochloride works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Bupivacaine hydrochloride works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Bupivacaine hydrochloride (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.