Phase 2b Study of EVO756 in Adults With Atopic Dermatitis

NCT07150845 · tracked via the Priya Life Science USA tracker

Sponsor

Evommune, Inc.

Phase

Phase 2

Started

2025-08-26

Last updated

2026-05-18

Condition(s) studied

Atoptic Dermatitis

Investigational drug(s) / intervention(s)

EVO756EVO756EVO756Placebo control

EVO756: Dose 1

EVO756: Dose 2

EVO756: Dose 3

Placebo control: Placebo control

Study summary

This study will evaluate the efficacy and safety of different doses of EVO756 in adults with moderate to severe atopic dermatitis.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Chronic AD that has been present for ≥6 months * Validated-Investigator's Global Assessment score of ≥3 * EASI of ≥16 * BSA of AD involvement of ≥10% Exclusion Criteria: * Any clinically significant abnormality in laboratory evaluations, physical examinations, vital signs, or ECG at Screening * Use of certain medications * Presence of skin comorbidities or other condition(s) that may interfere with study assessments * Significant AD flare, in the opinion of the Investigator, within 4 weeks prior to study entry

Primary outcome measure(s)

Percentage change in Eczema Area and Severity Index (EASI) from Baseline — Week 12

Trial sites (29)

Facility	City	Region
Saguaro Dermatology	Phoenix	Arizona
Center for Dermatology Clinical Research	Fremont	California
Metropolis Dermatology - Downtown Los Angeles	Los Angeles	California
Skin and Beauty Center	Pasadena	California
Skin Care Research, LLC	Boca Raton	Florida
Driven Research, LLC	Coral Gables	Florida
Skin Care Research - Hollywood Dermatology	Hollywood	Florida
TrueBlue Clinical Research	Tampa	Florida
DS Research	Clarksville	Indiana
Equity Medical	Bowling Green	Kentucky
Aesthetic and Dermatology Center	Rockville	Maryland
Great Lakes Research Group, Inc.	Bay City	Michigan
Revival Research Institute, LLC	Troy	Michigan
Michigan Dermatology Institute	Waterford	Michigan
MediSearch Clinical Trials	Saint Joseph	Missouri
Empire Dermatology	East Syracuse	New York
Equity Medical	New York	New York
Skin Search of Rochester, Inc.	Rochester	New York
Wilmington Dermatology Center	Wilmington	North Carolina
DOCS Dermatology Clinical Research	Canal Winchester	Ohio
International Clinical Research - Murfreesboro	Murfreesboro	Tennessee
Stryde Research	Lewisville	Texas
Progressive Clinical Research	San Antonio	Texas
Jordan Valley Dermatology Center	South Jordan	Utah
Pacific Clinical Research Network (PCRN) - Christchurch	Christchurch Central City	Christchurch
Optimal Clinical Trials	Auckland	NZL
Optimal Clinical Trials	Auckland	NZL
Clinical Trials NZ Limited	Hamilton	NZL
Momentum Clinical Research Lower Hutt	Lower Hutt	NZL

More Evommune, Inc. trials in the USA

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07150845 on ClinicalTrials.gov ↗ ← All trials in the USA