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Trackers› Clinical trials› California
Clinical trial register · United States · industry-sponsored

Clinical Trials in California, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 23 Sep 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4950
Recruiting now
open to new participants
2202
Lead sponsors
across recruiting studies
Top states
California 5295 Florida 4397 Illinois 2479 Georgia 2346 Arizona 2231
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca230 Eli Lilly and Company150 AbbVie142 Merck Sharp & Dohme LLC130 Novartis Pharmaceuticals113
State
California5295 Florida4397 Illinois2479 Georgia2346 Arizona2231
All 51 states
Target enrolment
to

Trials with a site in California

5295 of 9112 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Active, closed
The MOTION Study - Treatment of LSS With the MILD Procedure
NCT03610737Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Vertos Medical, Inc.
Not applicable
155
California, Colorado, Florida, Indiana, Kansas, Kentucky, Michigan, New Jersey
2018-08-02
Active, closed
Early Feasibility Study - Edwards APTURE Transcatheter Shunt System
NCT03523416Heart Failure
Edwards Lifesciences
Not applicable
71
California, Florida, Indiana, Kansas, Minnesota, New York, North Carolina, Ohio
2018-07-31
Active, closed
A Global Study to Assess the Effects of Osimertinib Following Chemoradiation in Patients With Stage III Unresectable Non-small Cell Lung Cancer (LAURA)
NCT03521154Non Small Cell Lung Cancer (Stage III)
AstraZeneca
Phase 3
216
California, Georgia, New Jersey, Utah, Wisconsin
2018-07-19
Recruiting
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
NCT03435796Neoplasms
Celgene
Phase 2/3
1,541
Alabama, Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia
2018-07-19
Active, closed
A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)
NCT03519945Ulcerative Colitis
Eli Lilly and Company
Phase 3
1,058
Alabama, Arizona, California, Florida, Georgia, Idaho, Illinois, Indiana
2018-07-18
Recruiting
A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)
NCT03592472Renal Cell Carcinoma
Xynomic Pharmaceuticals, Inc.
Phase 3
413
Arizona, California, Kentucky, Louisiana, Nebraska, New York, Ohio, Oregon
2018-07-17
Active, closed
Control of Myopia Using Novel Spectacle Lens Designs
NCT03623074Juvenile Myopia
SightGlass Vision, Inc.
Not applicable
266
California, Florida, Kansas, Louisiana, Missouri, New York, South Dakota, Tennessee
2018-07-16
Active, closed
X-linked Hypophosphatemia Disease Monitoring Program
NCT03651505X-linked Hypophosphatemia, Hypophosphatemic Rickets
Ultragenyx Pharmaceutical Inc
Observational
782
Alabama, California, Colorado, Connecticut, Illinois, Indiana, Maryland, Massachusetts
2018-07-16
Recruiting
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
NCT03178149Age-Related Macular Degeneration
Astellas Institute for Regenerative Medicine
Phase 1
42
Arizona, California, Florida, Georgia, Illinois, Massachusetts, Michigan, Mississippi
2018-07-13
Active, closed
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
NCT03451851Psoriasis
Janssen Research & Development, LLC
Phase 3
120
California, Georgia, Illinois, New Jersey, New York, Ohio, Texas
2018-07-11
Active, closed
ERG Components in Schizophrenia and Bipolar Disorder Type I
NCT03788811Schizophrenia, Bipolar I Disorder
diaMentis Inc.
Observational
300
California, Florida, Massachusetts, New Jersey, New York, Texas
2018-07-05
Active, closed
A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer
NCT03505320Pharmacokinetics of Zolbetuximab, Gastric Cancer, Gastro-esophageal Junction (GEJ) Cancer, Pharmacokinetics of Oxaliplatin
Astellas Pharma Global Development, Inc.
Phase 2
143
California, Illinois, Massachusetts, New York
2018-06-29
Active, closed
First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma
NCT03625037DLBCL, High-grade B-cell Lymphoma (HGBCL), Primary Mediastinal Large B-cell Lymphoma (PMBCL), FL
Genmab
Phase 1/2
666
Arizona, California, Colorado, Florida, Iowa, Louisiana, Michigan, Nebraska
2018-06-26
Active, closed
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors
NCT03485209Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung, Exocrine Pancreatic Cancer, Carcinoma, Squamous Cell of Head and Neck
Seagen, a wholly owned subsidiary of Pfizer
Phase 2
350
California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana, Kansas
2018-06-25
Active, closed
A Study to Compare Zolbetuximab (IMAB362) and Chemotherapy With Placebo and Chemotherapy in Adults With Gastric Cancer.
NCT03504397Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
Astellas Pharma Global Development, Inc.
Phase 3
565
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Kentucky
2018-06-21
Active, closed
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
NCT03433274Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases
Abbott Medical Devices
Not applicable
103
Alabama, Arizona, Arkansas, California, Colorado, Florida, Georgia, Idaho
2018-06-15
Active, closed
LTFU Study of Subjects With Cervical SCI Who Received AST-OPC1
NCT05975424Spinal Cord Injuries
Lineage Cell Therapeutics, Inc.
Observational
25
California, Georgia, Illinois, Pennsylvania, Wisconsin
2018-06-13
Active, closed
Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Have Not Received Previous Systemic Anticancer Therapy
NCT03755791Hepatocellular Carcinoma
Exelixis
Phase 3
837
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Maryland, Massachusetts
2018-06-10
Recruiting
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
NCT03556228Head and Neck Carcinoma, Adenoid Cystic Carcinoma, Lung Cancer, Non-Small Cell Lung Cancer
VM Oncology, LLC
Phase 1/2
242
California, Connecticut, District of Columbia, Florida, New Jersey, New Mexico, New York, Ohio
2018-06-08
Active, closed
INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)
NCT03491683Glioblastoma
Inovio Pharmaceuticals
Phase 1/2
52
California, Florida, Georgia, Massachusetts, Michigan, New Jersey, New York, North Carolina
2018-05-31
Active, closed
A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis
NCT03523858Progressive Multiple Sclerosis (PMS)
Hoffmann-La Roche
Phase 3
927
California, Florida, Illinois, Massachusetts, Michigan, Missouri, New York, Ohio
2018-05-28
Active, closed
A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
NCT03522246Epithelial Ovarian Cancer, Primary Peritoneal, Fallopian Tube Cancer, Newly Diagnosed
pharmaand GmbH
Phase 3
1,097
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana
2018-05-14
Active, closed
Oleclumab (MEDI9447) Epidermal Growth Factor Receptor Mutant (EGFRm) Non-small Cell Lung Cancer (NSCLC) Novel Combination Study
NCT03381274Carcinoma, Non-Small-Cell Lung
MedImmune LLC
Phase 1/2
43
California, Colorado, Connecticut, Georgia, Illinois, Maryland, New York, Texas
2018-05-08
By invitation
A Multicenter, Post-Market Clinical Follow-up Study of Subjects With the REDAPT™ System Monolithic Sleeveless/Sleeved Stem and/or Fully Porous Acetabular Shell With XLPE Liner and/or Modular Shell Components Previously Implanted
NCT03610789Hip Replacement
Smith & Nephew, Inc.
Observational
220
California, New York
2018-05-07
Active, closed
Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome
NCT03604198Cushing Syndrome
Corcept Therapeutics
Phase 2
125
Arizona, California, Florida, Georgia, Illinois, Indiana, Louisiana, Maryland
2018-05-07
Active, closed
Extended Access of Momelotinib in Adults With Myelofibrosis
NCT03441113Neoplasms, Post-polycythemia Vera Myelofibrosis (Post-PV MF), Primary Myelofibrosis (PMF), Post-essential Thrombocythemia Myelofibrosis (Post-ET MF)
GlaxoSmithKline
Phase 2
237
Arizona, California, Colorado, Florida, Georgia, Maryland, Massachusetts, Minnesota
2018-05-03
Recruiting
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
NCT03526835Advanced/Metastatic Solid Tumors, Colorectal Cancer, Gastric Cancer, Gastroesophageal-junction Cancer
Merus B.V.
Phase 1/2
560
California, Colorado, Florida, Georgia, Massachusetts, Michigan, Missouri, New York
2018-05-02
Active, closed
P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion With Instrumentation
NCT03438747Degenerative Disc Disease
CeraPedics, Inc
Not applicable
290
Alabama, California, Colorado, Connecticut, Florida, Illinois, Indiana, Kentucky
2018-04-24
Active, closed
Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)
NCT03425643Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC
Phase 3
797
Arizona, California, Connecticut, Delaware, Florida, Georgia, Illinois, Indiana
2018-04-24
Active, closed
Pyruvate Kinase Deficiency Global Longitudinal Registry
NCT03481738Pyruvate Kinase Deficiency
Agios Pharmaceuticals, Inc.
Observational
500
Arizona, Arkansas, California, Georgia, Massachusetts, Michigan, North Carolina, Pennsylvania
2018-04-23
Active, closed
THE ALIGN-AR EFS TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study
NCT02732704Aortic Regurgitation
JenaValve Technology, Inc.
Not applicable
100
California, District of Columbia, Georgia, Michigan, New York, Texas, Washington
2018-04-20
Active, closed
A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation
NCT03383458Hepatocellular Carcinoma, Liver Cancer
Bristol-Myers Squibb
Phase 3
545
Alabama, Arizona, California, Colorado, Florida, Georgia, Kansas, Louisiana
2018-04-18
Active, closed
The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration
NCT03348995Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Miach Orthopaedics
Not applicable
250
California, Florida, Georgia, Louisiana, Maryland, Massachusetts, New Jersey, Rhode Island
2018-04-17
Recruiting
A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
NCT03460977Metastatic Castration Resistant Prostate Cancer (mCRPC), Small Cell Lung Cancer (SCLC), Follicular Lymphoma (FL)
Pfizer
Phase 1
453
Arizona, California, Connecticut, Kansas, Kentucky, Maryland, Massachusetts, Nebraska
2018-04-17
Active, closed
A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease
NCT03466411Crohn's Disease
Janssen Research & Development, LLC
Phase 2/3
1,409
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2018-04-13
Active, closed
A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma
NCT03470922Melanoma
Bristol-Myers Squibb
Phase 2/3
714
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Indiana, Maryland
2018-04-11
Active, closed
Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667)
NCT03407144Hodgkin Lymphoma
Merck Sharp & Dohme LLC
Phase 2
340
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, District of Columbia, Florida
2018-04-09
Active, closed
A Study of the Efficacy and Safety of Risankizumab in Participants With Crohn's Disease
NCT03105102Crohn's Disease
AbbVie
Phase 3
1,336
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia, Illinois
2018-04-09
Active, closed
Study of Patients Receiving DUPIXENT® for Atopic Dermatitis (AD)
NCT03428646Dermatitis, Atopic
Regeneron Pharmaceuticals
Observational
858
Alabama, Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana
2018-04-06
Active, closed
Study of the Safety and Effectiveness of Motiva Implants®
NCT03579901Breast Implants
Motiva USA LLC
Not applicable
800
California, Colorado, Georgia, Illinois, Indiana, Kentucky, Louisiana, Michigan
2018-04-06
Recruiting
Non-invasive Liquid Biopsy Analysis of Epigenomics Signatures in Multiple Cancer Types
NCT03869814Diagnosis of Cancer of Various Organs
ClearNote Health
Observational
20,000
California
2018-04-05
Recruiting
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
NCT03424005Metastatic Breast Cancer
Hoffmann-La Roche
Phase 1/2
1,132
California, Colorado, Florida, Illinois, Minnesota, Nevada, New Jersey, New York
2018-03-30
Active, closed
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
NCT03390504Urothelial Cancer
Janssen Research & Development, LLC
Phase 3
629
Alaska, California, District of Columbia, Florida, Georgia, Illinois, Kentucky, Maryland
2018-03-23
Active, closed
A Phase III, Safety, Tolerability and Efficacy of Combination Treatment of BL-8040 and Granulocyte Colony Stimulating Factor (G-CSF) as Compared to Placebo and G-CSF for the Mobilization of Hematopoietic Stem Cells for Autologous Transplantation in Subjects With Multiple Myeloma (MM)
NCT03246529Multiple Myeloma
BioLineRx, Ltd.
Phase 3
180
California, Florida, Illinois, Maryland, Minnesota, Missouri, Ohio, Texas
2018-03-23
Active, closed
A Phase 1 Dose-escalation Study of FF-10832 for Treatment of Solid Tumors Including Biliary Tract Cancer
NCT03440450Advanced Solid Tumors, Biliary Tract Cancer
Fujifilm Pharmaceuticals U.S.A., Inc.
Phase 1
90
Arizona, California, Colorado, Tennessee, Texas, Washington
2018-03-22
Active, closed
A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433
NCT03345823Crohn's Disease
AbbVie
Phase 3
747
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Idaho
2018-03-21
By invitation
Compliant Analysis of Patient Samples and Data
NCT04364503Pregnancy Related, Cancer, Infectious Disease
Sequenom, Inc.
Observational
2,000
California, Colorado, Illinois, New York, North Carolina
2018-03-17
Active, closed
A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine
NCT03432286Episodic Migraine
Eli Lilly and Company
Phase 3
533
Alabama, Arizona, California, Colorado, Florida, Georgia, Idaho, Illinois
2018-03-14
Recruiting
Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC
NCT03257033Locally Advanced Pancreatic Cancer
RenovoRx
Phase 3
190
California, Colorado, District of Columbia, Florida, Georgia, Iowa, Louisiana, Maryland
2018-03-12
Recruiting
The PREDICT Registry:
NCT03448926DCIS, Stage 0 Breast Cancer, Ductal Breast Carcinoma In Situ
PreludeDx
Observational
3,000
Arizona, California, Colorado, Florida, Georgia, Illinois, Maryland, Massachusetts
2018-02-27
Active, closed
ExAblate Pallidotomy for Medically-Refractory Dyskinesia Symptoms or Motor Fluctuations of Advanced Parkinson's Disease
NCT03319485Parkinson Disease
InSightec
Not applicable
92
California, Florida, Maryland, Massachusetts, Minnesota, New York, Ohio, Pennsylvania
2018-02-09
Active, closed
AMPLATZER PFO Occluder Post Approval Study
NCT03309332Stroke, Patent Foramen Ovale
Abbott Medical Devices
Not applicable
1,214
Alabama, Arizona, Arkansas, California, Colorado, District of Columbia, Florida, Georgia
2018-01-31
Active, closed
First-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01)
NCT03401385Hormone Receptor Positive Breast Cancer, Triple Negative Breast Cancer, Non-small Cell Lung Cancer
Daiichi Sankyo Co., Ltd.
Phase 1
890
California, District of Columbia, Georgia, Maryland, Massachusetts, New York, Tennessee, Texas
2018-01-31
Recruiting
Mucopolysaccharidosis VII Disease Monitoring Program
NCT03604835Mucopolysaccharidosis VII, MPS VII, MPS 7, Sly Syndrome
Ultragenyx Pharmaceutical Inc
Observational
50
California, District of Columbia, Illinois, Michigan, New York, Utah, Washington
2018-01-29
Active, closed
Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients
NCT02922036Heart Failure
EBR Systems, Inc.
Not applicable
300
Alabama, California, Florida, Georgia, Illinois, Indiana, Iowa, Kansas
2018-01-17
Active, closed
Study of IMGN632 in Patients With Untreated BPDCN and Relapsed/Refractory BPDCN
NCT03386513Blastic Plasmacytoid Dendritic Cell Neoplasm, Myeloproliferative Neoplasm
AbbVie
Phase 1/2
179
Alabama, Arizona, California, Florida, Maryland, Massachusetts, New York, North Carolina
2018-01-02
Recruiting
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
NCT03452774Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver
Massive Bio, Inc.
Observational
50,000
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida
2018-01-01
Recruiting
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
NCT03142152Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases
Cardiac Dimensions, Inc.
Not applicable
300
Arizona, California, Colorado, District of Columbia, Florida, Georgia, Illinois, Indiana
2018-01-01
Recruiting
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy
NCT03394365Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant
Pierre Fabre Medicament
Phase 3
115
California, Connecticut, District of Columbia, Florida, Georgia, Illinois, Maryland, Massachusetts
2017-12-29
Recruiting
CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)
NCT03328078Relapsed Hematologic Malignancy, Refractory Hematologic Malignancy, Relapsed Primary Central Nervous System Lymphoma, Refractory Primary Central Nervous System Lymphoma
Curis, Inc.
Phase 1/2
152
Arizona, California, Connecticut, Florida, Illinois, Massachusetts, Minnesota, Nebraska
2017-12-28
Active, closed
Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC)
NCT03319940Small Cell Lung Carcinoma
Amgen
Phase 1
269
California, Connecticut, Florida, Georgia, Illinois, Louisiana, Maryland, Michigan
2017-12-26
Active, closed
Assessment of the GORE® EXCLUDER® Conformable AAA Endoprosthesis in the Treatment of Abdominal Aortic Aneurysms
NCT02489539Aortic Aneurysm, Abdominal
W.L.Gore & Associates
Not applicable
175
Alabama, Arizona, California, Florida, Georgia, Illinois, Iowa, Louisiana
2017-12-19
Active, closed
Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy
NCT03334617Non-Small Cell Lung Cancer
AstraZeneca
Phase 2
528
California, District of Columbia, Illinois, Maryland, Massachusetts, Missouri, New York, Pennsylvania
2017-12-18
Active, closed
Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC
NCT03395197mCRPC
Pfizer
Phase 3
1,054
Alaska, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2017-12-18
Active, closed
Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma
NCT03399799Hematological Malignancies
Janssen Research & Development, LLC
Phase 1
279
Alabama, California, Colorado, New York, Tennessee
2017-12-16
Active, closed
Study of the RelayPro Thoracic Stent-Graft in Subjects With an Acute, Complicated Type B Aortic Dissection
NCT03033043Aortic Dissection Type B
Bolton Medical
Not applicable
56
California, Colorado, Connecticut, District of Columbia, Georgia, Illinois, Indiana, Iowa
2017-12-14
Active, closed
An Extension Study to Evaluate the Efficacy and Safety of BMN 111 in Children With Achondroplasia
NCT03424018Achondroplasia
BioMarin Pharmaceutical
Phase 3
119
California, Delaware, Georgia, Illinois, Maryland, Missouri, Ohio, Texas
2017-12-12
Active, closed
Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)
NCT03301506Primary Biliary Cirrhosis
Gilead Sciences
Phase 3
340
Arkansas, California, Colorado, Connecticut, Florida, Georgia, Illinois, Louisiana
2017-12-12
Active, closed
Microdystrophin Gene Transfer Study in Adolescents and Children With DMD
NCT03368742Duchenne Muscular Dystrophy
Solid Biosciences Inc.
Phase 1/2
12
California, Florida
2017-12-06
Active, closed
Early Feasibility Study of the RelayBranch Thoracic Stent-Graft System
NCT03214601Thoracic Aorta Aneurysm, Aneurysm, Ruptured, Aortic Aneurysm
Bolton Medical
Not applicable
30
California, Florida, Georgia, Maryland, Massachusetts, Missouri, New York, North Carolina
2017-12-04
Active, closed
Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)
NCT03331198Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Small Lymphocytic
Juno Therapeutics, a Subsidiary of Celgene
Phase 1/2
320
Alabama, Arizona, California, Colorado, District of Columbia, Florida, Georgia, Illinois
2017-11-27
Active, closed
Early Feasibility Study of the Orion Visual Cortical Prosthesis System
NCT03344848Blindness, Acquired
Second Sight Medical Products
Not applicable
6
California, Texas
2017-11-20
Active, closed
U3-1402 in Metastatic or Unresectable Non-Small Cell Lung Cancer
NCT03260491Non-Small Cell Lung Cancer (NSCLC)
Daiichi Sankyo
Phase 1
312
California, Georgia, Massachusetts, Michigan, New York, Ohio, Pennsylvania, Tennessee
2017-10-30
Active, closed
Efficacy, Safety and Tolerability Study of Long-acting Cabotegravir Plus Long-acting Rilpivirine (CAB LA + RPV LA) in Human-immunodeficiency Virus-1 (HIV-1) Infected Adults
NCT03299049HIV Infections
ViiV Healthcare
Phase 3
1,049
Alabama, Arizona, California, Colorado, District of Columbia, Florida, Georgia, Illinois
2017-10-27
Recruiting
Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study
NCT03373968Duchenne Muscular Dystrophy
Italfarmaco
Phase 2/3
206
California, Connecticut, Florida, Georgia, Iowa, Missouri, Oregon, Pennsylvania
2017-10-24
Recruiting
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
NCT03242642Mitral Valve Regurgitation
Medtronic Cardiovascular
Not applicable
1,056
Alabama, Arizona, California, Connecticut, District of Columbia, Florida, Georgia, Illinois
2017-10-23
Active, closed
Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma
NCT03298451Hepatocellular Carcinoma
AstraZeneca
Phase 3
1,324
California, District of Columbia, Florida, Kansas, Maryland, Michigan, Minnesota, New York
2017-10-11
Recruiting
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
NCT03175224Solid Tumors, Advanced Cancer, Renal Cancer, Gastric Cancer
Apollomics Inc.
Phase 2
497
California, Florida, Massachusetts, North Carolina, Pennsylvania, Wisconsin
2017-09-27
Active, closed
A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)
NCT03178552Non-Small Cell Lung Cancer
Hoffmann-La Roche
Phase 2/3
1,000
California, Colorado, Florida, Kentucky, Nevada, New Hampshire, New York, Oregon
2017-09-22
Active, closed
A Study in Participants Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study (IMbrella A)
NCT03148418Cancer
Hoffmann-La Roche
Phase 3
382
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Illinois
2017-09-20
Active, closed
Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE)
NCT03767348Non-Small Cell Lung Cancer (NSCLC), Microsatellite Instability-High (MSI-H), Non-melanoma Skin Cancer (NMSC), Cutaneous Melanoma
Replimune, Inc.
Phase 2
340
Alabama, Arizona, Arkansas, California, Florida, Iowa, Kentucky, Minnesota
2017-09-20
Active, closed
ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population
NCT03153449Primary Knee Arthroplasty
DePuy Orthopaedics
Not applicable
400
California, Colorado, Connecticut, Florida, Kentucky, Mississippi, New Hampshire, New Jersey
2017-09-19
Active, closed
SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation
NCT03230747Mitral Regurgitation, Mitral Disease
Edwards Lifesciences
Not applicable
72
California, Georgia, Illinois, Michigan, Minnesota, Utah, Virginia
2017-09-14
Active, closed
Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors
NCT03170960Urothelial Carcinoma, Renal Cell Carcinoma, Non-Small Cell Lung Cancer, Castration-resistant Prostate Cancer
Exelixis
Phase 1
914
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Illinois
2017-09-05
Active, closed
BioVentrix Revivent TC™ System Clinical Study
NCT02931240Ventricular Dysfunction, Left
BioVentrix
Not applicable
126
Arizona, California, Florida, Georgia, Illinois, Louisiana, Michigan, Minnesota
2017-08-29
Active, closed
Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
NCT02962414Tuberous Sclerosis Complex
Novartis Pharmaceuticals
Phase 3
206
Arizona, California, Colorado, Connecticut, Illinois, Minnesota, New Jersey, Ohio
2017-08-23
Active, closed
ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent
NCT03130777Pulmonary Disease, Transcatheter Pulmonary Valve Replacement (TPVR), Tetralogy of Fallot, Congenital Heart Disease
Edwards Lifesciences
Not applicable
86
California, Colorado, Georgia, Missouri, New York, Ohio, Pennsylvania, Texas
2017-08-22
Active, closed
Personalized Therapy Study - Attain Stability Quad Post-Approval Study
NCT04024943Heart Failure
Medtronic
Observational
1,092
Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia
2017-08-21
Recruiting
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)
NCT03016819Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma, Soft-Tissue Sarcoma
Advenchen Laboratories, LLC
Phase 3
325
Arizona, California, Colorado, Florida, Illinois, Michigan, Minnesota, Missouri
2017-08-15
Active, closed
Safety, Tolerability, and Immunogenicity of mRNA-4157 Alone and in Combination in Participants With Solid Tumors
NCT03313778Solid Tumors
ModernaTX, Inc.
Phase 1
161
California, District of Columbia, Florida, Massachusetts, New York, Ohio, Pennsylvania, Texas
2017-08-14
Active, closed
A Study of AT132 in Young Children With X-Linked Myotubular Myopathy (XLMTM)
NCT03199469X-Linked Myotubular Myopathy
Astellas Gene Therapies
Phase 2/3
27
California, Illinois, Maryland
2017-08-02
Active, closed
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma
NCT02704858Glioblastoma Multiforme
Neonc Technologies, Inc.
Phase 1/2
49
California, Georgia, Louisiana, New Jersey, New York, North Carolina, Ohio, Texas
2017-08-01
Active, closed
JOURNEY II XR Safety and Effectiveness PMCF
NCT03136887Rheumatoid Vasculitis With Rheumatoid Arthritis of Knee, Unilateral Post-Traumatic Osteoarthritis of Knee, Knee Osteoarthritis, Degenerative Arthritis Peripheral Joint
Smith & Nephew, Inc.
Observational
176
California, Florida, Illinois, Maryland, Michigan, Nevada, New Jersey, New York
2017-07-28
Active, closed
Study of E7386 in Participants With Selected Advanced Neoplasms
NCT03264664Advanced Neoplasms
Eisai Inc.
Phase 1
60
Arizona, California, Florida, Minnesota, Texas
2017-07-27
Active, closed
Study of Iopofosine I-131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) With Expansion in Waldenstrom
NCT02952508Waldenstrom Macroglobulinemia, Multiple Myeloma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Cellectar Biosciences, Inc.
Phase 2
120
California, District of Columbia, Florida, Georgia, Illinois, Kansas, Louisiana, Maryland
2017-07-26
Active, closed
Savolitinib vs. Sunitinib in MET-driven PRCC.
NCT03091192Carcinoma, Carcinoma, Renal Cell, Kidney Neoplasms, Urologic Neoplasms
AstraZeneca
Phase 3
60
California, Georgia, Illinois, Iowa, Massachusetts, Missouri, New York, Tennessee
2017-07-25
Active, closed
A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease
NCT03251118Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis, Indeterminate Colitis
Target PharmaSolutions, Inc.
Observational
15,000
California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa, Louisiana
2017-07-24
Active, closed
ADAPT - A Patient Registry of the Real-world Use of Orenitram®
NCT03045029Pulmonary Arterial Hypertension
United Therapeutics
Observational
300
California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa, Kentucky
2017-07-18
Active, closed
LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis
NCT03115983Degenerative Spondylolisthesis, Lumbar Spinal Stenosis
Empirical Spine, Inc.
Not applicable
299
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kentucky
2017-07-17
Active, closed
EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis
NCT03042104Heart Diseases, Aortic Stenosis, Severe
Edwards Lifesciences
Not applicable
901
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Illinois
2017-07-12
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 24 September 2026. https://priyalifescience.com/clinical-trials-usa/state/california?page=51

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,112 studies in total at the last sync on 23 Sep 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 5,295 of those studies with a site in California.

How many clinical trials are recruiting in California?

2,760 of the 5,295 studies on this page are recruiting new participants as of the 23 Sep 2026, 03:16 UTC sync. A further 162 have not yet opened recruitment, 2,205 are active but closed to new participants, and 168 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.