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Trackers› Clinical trials› California
Clinical trial register · United States · industry-sponsored

Clinical Trials in California, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9115 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 24 Sep 2026, 03:16 UTC
9115
Studies in scope
industry-sponsored, all four open statuses
4955
Recruiting now
open to new participants
2206
Lead sponsors
across recruiting studies
Top states
California 5299 Florida 4396 Illinois 2477 Georgia 2346 Arizona 2230
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca230 Eli Lilly and Company150 AbbVie142 Merck Sharp & Dohme LLC129 Novartis Pharmaceuticals113
State
California5299 Florida4396 Illinois2477 Georgia2346 Arizona2230
All 51 states
Target enrolment
to

Trials with a site in California

5299 of 9115 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
Dazucorilant in Patients With Amyotrophic Lateral Sclerosis
NCT05407324Amyotrophic Lateral Sclerosis
Corcept Therapeutics
Phase 2
279
Arizona, California, New Jersey, New York
2022-11-15
Active, closed
Safety and Effectiveness of the TENEO 317 Model 2 (1.28 US) Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Hyperopia With or Without Astigmatism
NCT05264623Hyperopia
Bausch & Lomb Incorporated
Not applicable
140
California, Florida, Minnesota, Nebraska, New York, Pennsylvania, South Dakota, Texas
2022-11-15
Active, closed
Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-Line Treatment in Participants With PD-L1-Positive (CPS โ‰ฅ 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck
NCT05287113Head and Neck Cancer
Incyte Biosciences International Sร rl
Phase 2
176
Arizona, California, District of Columbia, Florida, Illinois, Iowa, Kansas, Maryland
2022-11-14
By invitation
EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study
NCT05610787Heart Failure, Transplant; Failure, Heart, Congenital Heart Disease
Berlin Heart, Inc
Not applicable
40
California, Colorado, District of Columbia, Florida, Illinois, Massachusetts, Michigan, Missouri
2022-11-14
Recruiting
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
NCT05498428Carcinoma, Non-small-Cell Lung
Janssen Research & Development, LLC
Phase 2
520
California, District of Columbia, Florida, Kansas, Maryland, Massachusetts, Missouri, New Jersey
2022-11-11
Active, closed
Asciminib Monotherapy, With Dose Escalation, for 2nd and 1st Line Chronic Myelogenous Leukemia
NCT05384587Chronic Myelogenous Leukemia - Chronic Phase
Novartis Pharmaceuticals
Phase 2
34
Alabama, Alaska, Arizona, California, Colorado, Connecticut, Florida, Georgia
2022-11-11
Active, closed
Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis
NCT05583227Eosinophilic Esophagitis
AstraZeneca
Phase 3
368
Arizona, Arkansas, California, Colorado, Florida, Illinois, Iowa, Kansas
2022-11-10
Active, closed
Embody Post-Market Clinical Follow-Up Study
NCT05735119Tendon Injuries- Subscapularis
Zimmer Biomet
Observational
100
California, Florida, Indiana, Kentucky
2022-11-09
Recruiting
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
NCT05457283Chronic Kidney Disease, Proteinuria, Children
Bayer
Phase 3
100
Arizona, California, District of Columbia, Florida, Georgia, Iowa, Maryland, Massachusetts
2022-11-08
Recruiting
A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered Foam Dressing
NCT05608317Wounds, Wound of Skin, Wound Leg, Venous Leg Ulcer
Molnlycke Health Care AB
Not applicable
20
California, Florida, Pennsylvania
2022-11-08
Active, closed
A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy
NCT05444257Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
Phase 3
822
Alabama, Arizona, Arkansas, California, Colorado, Florida, Georgia, Idaho
2022-11-08
Active, closed
A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)
NCT05490446Myelodysplastic Syndromes
Agios Pharmaceuticals, Inc.
Phase 2
87
California, Connecticut, Florida, Illinois, Missouri, New York, North Carolina
2022-11-07
Recruiting
Clinical Trial to Compare the Efficacy of Celiprolol to Placebo in Patients With Vascular Ehlers-Danlos Syndrome
NCT05432466Vascular Ehlers-Danlos Syndrome
Acer Therapeutics Inc.
Phase 3
150
California
2022-11-07
Active, closed
LAMBDA 002 (Lung Registry) Study
NCT05170425Lung Transplant Rejection
Natera, Inc.
Observational
154
California, Illinois, Maryland, Michigan, Missouri, New York, Ohio, Texas
2022-11-04
Active, closed
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
NCT05567796Obesity
Novo Nordisk A/S
Phase 3
3,400
Alabama, California, Colorado, Florida, Georgia, Hawaii, Illinois, Indiana
2022-11-01
Active, closed
An Open-Label Extension Study of BPN14770 in Subjects With Fragile X Syndrome
NCT05367960Fragile X Syndrome
Tetra Discovery Partners
Phase 3
314
California, Colorado, Florida, Georgia, Illinois, Kansas, Maryland, Massachusetts
2022-11-01
Active, closed
Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type
NCT05397639Agitation, Alzheimer's Type Dementia
Suven Life Sciences Limited
Phase 3
375
California, Connecticut, Florida, Illinois, New Jersey, New York, Ohio, South Carolina
2022-11-01
Recruiting
A Phase 1/3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation
NCT05473910AML, MDS
TScan Therapeutics, Inc.
Phase 1
310
California, Colorado, Connecticut, Florida, Georgia, Maryland, Massachusetts, Michigan
2022-11-01
Active, closed
A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors
NCT05585320Advanced Solid Tumor, Pancreatic Adenocarcinoma, Malignant Melanoma (Cutaneous), Non-small Cell Lung Cancer (NSCLC)
Immuneering Corporation
Phase 1/2
209
Arizona, California, Colorado, Florida, Illinois, Massachusetts, Minnesota, New York
2022-10-31
Recruiting
A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilexยฎ Up as the Primary Dressing.
NCT05588583Wounds, Wound of Skin, Wound Leg, Wound; Foot
Molnlycke Health Care AB
Not applicable
68
California, Florida, Pennsylvania
2022-10-31
Active, closed
A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH
NCT05389449Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc.
Phase 3
80
California, Illinois, Maryland, Missouri, New York, Ohio, Texas
2022-10-28
Recruiting
A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting
NCT05452941Pneumonia
Pfizer
Observational
12,500
California, Connecticut, District of Columbia, Georgia, Kentucky, Louisiana, Maryland, Massachusetts
2022-10-27
Active, closed
EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
NCT05284747Cardiovascular Disease, Myocardial Infarction, Stroke, Coronary Revascularization
Amgen
Phase 4
6,019
Alabama, Arizona, California, Colorado, Connecticut, Florida, Idaho, Illinois
2022-10-26
Active, closed
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma
NCT05169515Non-Hodgkin Lymphoma
Hoffmann-La Roche
Phase 1
121
California, Colorado, Florida, Illinois, North Carolina, Texas
2022-10-26
Active, closed
BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors
NCT05120271Hepatocellular Carcinoma, Squamous Cell Carcinoma of the Lung, Merkel Cell Carcinoma, Myxoid/Round Cell Liposarcoma
Sotio Biotech Inc.
Phase 1/2
7
California, Texas, Washington, Wisconsin
2022-10-26
Recruiting
A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors
NCT05536141Clear Cell Renal Cell Carcinoma, Solid Tumors
Arcus Biosciences, Inc.
Phase 1
362
Alabama, California, Florida, Georgia, Kentucky, Louisiana, Maryland, Massachusetts
2022-10-26
Recruiting
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
NCT05552222Multiple Myeloma
Janssen Research & Development, LLC
Phase 3
1,590
Arizona, California, Connecticut, Delaware, Florida, Georgia, Illinois, Iowa
2022-10-25
Recruiting
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
NCT05208762Carcinoma, Non-Small-Cell Lung, Squamous Cell Carcinoma of the Head and Neck, Esophageal Squamous Cell Carcinoma, Triple Negative Breast Neoplasms
Seagen, a wholly owned subsidiary of Pfizer
Phase 1
714
Alabama, California, Iowa, Michigan, Ohio, Texas, Utah, Virginia
2022-10-25
Active, closed
The GOREยฎ VIABAHNยฎ FORTEGRA Venous Stent IVC Study
NCT05409976Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
W.L.Gore & Associates
Not applicable
136
California, District of Columbia, Illinois, Michigan, New York, North Carolina, Virginia
2022-10-25
Recruiting
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
NCT05253651Colorectal Neoplasms
Seagen, a wholly owned subsidiary of Pfizer
Phase 3
400
Arizona, California, Colorado, Florida, Georgia, Kansas, Kentucky, Minnesota
2022-10-24
Active, closed
The MONARCH Case Series Study: SPRINTยฎ Peripheral Nerve Stimulation for the Treatment of Head Pain
NCT05491915Cervicogenic Headache, Occipital Neuralgia
SPR Therapeutics, Inc.
Not applicable
50
California, Massachusetts, Minnesota, North Carolina, Texas, Utah
2022-10-24
Active, closed
A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX)
NCT05540860Duchenne Muscular Dystrophy
Edgewise Therapeutics, Inc.
Phase 2
76
Arkansas, California, Colorado, Florida, Georgia, Iowa, Kansas, Maryland
2022-10-24
Active, closed
An Early Feasibility Study Evaluating the Safety and Efficacy of the Laminar Left Atrial Appendage Closure System in Subjects With Non-Valvular Atrial Fibrillation
NCT05565599Non-valvular Atrial Fibrillation
Biosense Webster, Inc.
Not applicable
58
Arizona, Arkansas, California, New York
2022-10-21
Active, closed
Abbott Atrial Fibrillation Post Approval Study
NCT05434650Atrial Arrhythmia, Atrium; Fibrillation, Atrial Tachycardia
Abbott Medical Devices
Observational
200
Alabama, Arkansas, California, Georgia, Louisiana, Massachusetts, Michigan, Mississippi
2022-10-21
Active, closed
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
NCT05581004Locally Advanced or Metastatic Solid Tumors, NSCLC, HNSCC, Melanoma
Genentech, Inc.
Phase 1
165
California, Colorado, Florida, Georgia, Massachusetts, Missouri, New Jersey, Tennessee
2022-10-20
Active, closed
A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension
NCT05203510Pulmonary Arterial Hypertension
United Therapeutics
Phase 4
52
Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana, Massachusetts
2022-10-20
Active, closed
A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis
NCT05559359Atopic Dermatitis, Eczema
Eli Lilly and Company
Phase 3
377
Alabama, Arizona, Arkansas, California, Connecticut, Florida, Idaho, Illinois
2022-10-18
Active, closed
Clinical Study of DTX301 AAV-Mediated Gene Transfer for Ornithine Transcarbamylase (OTC) Deficiency
NCT05345171OTC Deficiency
Ultragenyx Pharmaceutical Inc
Phase 3
37
California, Colorado, Illinois, Ohio
2022-10-18
Active, closed
A Study About the Natural History in Adults With BAG3 Dilated Cardiomyopathy (a Type of Heart Disease) (BAG3 DCM)
NCT05981092Cardiomyopathy, Dilated, Bcl-2 Anathogene-3 (BAG3) Dilated Cardiomyopathy (DCM)
Alexion Pharmaceuticals, Inc.
Observational
35
California, Colorado, Massachusetts, Minnesota, New York, Pennsylvania
2022-10-14
Recruiting
International Multicentric Observational Study to Characterize Subpopulations of Patients With Autism Spectrum Disorder
NCT05590715Autism Spectrum Disorder
Stalicla SA
Observational
1,500
Arizona, California, Florida, Illinois, Missouri, New Mexico, Texas, Utah
2022-10-13
Active, closed
Study of Oral MRT-2359 in Selected Cancer Patients
NCT05546268NSCLC, SCLC, High Grade Neuroendocrine Cancer, DLBCL
Monte Rosa Therapeutics, Inc
Phase 1/2
174
Arizona, California, Connecticut, Kansas, Massachusetts, Michigan, Missouri, New York
2022-10-12
Recruiting
Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC
NCT05491525Neurogenic Detrusor Overactivity
Urovant Sciences GmbH
Phase 2/3
71
Arkansas, California, Colorado, Florida, Kansas, Louisiana, New York, North Carolina
2022-10-12
Active, closed
Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer
NCT05502237Non-small Cell Lung Cancer
Gilead Sciences
Phase 3
1,021
California, District of Columbia, Florida, Illinois, North Carolina, Ohio, Oregon, Pennsylvania
2022-10-12
Active, closed
A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity
NCT05556512Obesity, Overweight
Eli Lilly and Company
Phase 3
15,374
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia, Hawaii
2022-10-11
Active, closed
Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC
NCT05595460SCLC,Extensive Stage
RayzeBio, Inc.
Phase 1
21
California, Florida, Iowa, Kentucky, Michigan, Minnesota, Missouri, Nebraska
2022-10-10
Active, closed
A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815
NCT05557045Advanced Cancer, Metastatic Cancer, Solid Tumor, Melanoma
Jazz Pharmaceuticals
Phase 1
98
California, Colorado, Florida, Illinois, New York, Oklahoma, Pennsylvania, Tennessee
2022-10-10
Active, closed
A Study of NX-019 in Patients with Advanced, Epidermal Growth Factor Receptor (EGFR) Mutant Cancer
NCT05514496EGFR Mutation-Related Tumors
Nalo Therapeutics Inc.
Phase 1
258
California, Minnesota, Virginia
2022-10-05
Active, closed
Study of the Adverse Events and Change in Disease State of Pediatric Participants (and Young Adults Between the Ages of 18-25) With Relapsed/Refractory Aggressive Mature B-cell Neoplasms Receiving Subcutaneous (SC) Injections of Epcoritamab
NCT05206357Non-hodgkin Lymphoma
Genmab
Phase 1
17
California, Florida, New York, North Carolina, Ohio, Pennsylvania, Tennessee, Texas
2022-10-04
Active, closed
A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies
NCT05453903Leukemia, Myeloid, Acute
Janssen Research & Development, LLC
Phase 1
196
Alabama, California, Massachusetts, New York, North Carolina, Texas
2022-10-04
Active, closed
RNS System LGS Feasibility Study
NCT05339126Epilepsy, Lennox Gastaut Syndrome, Lennox-Gastaut Syndrome, Intractable, Seizures
NeuroPace
Phase 2
24
Alabama, California, Georgia, Massachusetts, New York
2022-10-04
Active, closed
A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer
NCT05514054Breast Neoplasms
Eli Lilly and Company
Phase 3
8,000
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, District of Columbia, Florida
2022-10-04
Active, closed
Study to Assess the Safety of DERMASEAL for Diabetic Foot Ulcers
NCT05586542Foot Ulcer, Diabetic
Vitruvian Medical Devices, Inc.
Phase 1
26
California, Florida, Ohio, Texas
2022-10-03
Recruiting
Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy
NCT05283226Carcinoma, Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma
NATCO Pharma Ltd.
Phase 2
21
California, Florida, Kentucky, Maryland, Missouri, New Hampshire, Pennsylvania, Wisconsin
2022-09-30
Recruiting
A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancies
NCT05443126NSCLC
Ellipses Pharma
Phase 1/2
265
California, District of Columbia, Florida, Illinois, Kentucky, Massachusetts, Michigan, New York
2022-09-30
Active, closed
Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)
NCT05509023Atopic Dermatitis
Q32 Bio Inc.
Phase 2
102
Alabama, California, Florida, Georgia, Idaho, Illinois, Indiana, Maryland
2022-09-30
Active, closed
A Single-arm, Multicenter Study to Assess the Efficacy, Safety, and Tolerability of P1101 in Adults With ET
NCT05482971Essential Thrombocythemia
PharmaEssentia
Phase 2
91
Alabama, California, Connecticut, District of Columbia, Georgia, Indiana, Kentucky, Louisiana
2022-09-29
Active, closed
Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRฮฑ) Expressing, Platinum-sensitive Epithelial Ovarian Cancer
NCT05456685High Grade Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer
AbbVie
Phase 2
125
Arizona, California, Connecticut, Florida, Georgia, Illinois, Louisiana, Massachusetts
2022-09-28
Active, closed
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Satralizumab in Participants With Anti-N-methyl-D-aspartic Acid Receptor (NMDAR) or Anti-leucine-rich Glioma-inactivated 1 (LGI1) Encephalitis
NCT05503264NMDAR Autoimmune Encephalitis, LGI1 Autoimmune Encephalitis
Hoffmann-La Roche
Phase 3
122
Alabama, California, Colorado, District of Columbia, Georgia, Maryland, Massachusetts, Minnesota
2022-09-27
Recruiting
Post-Market Study to Assess iTind Safety in Comparison to UroLift
NCT04757116Benign Prostatic Hyperplasia (BPH)
Olympus Corporation of the Americas
Not applicable
256
Arizona, California, Illinois, Louisiana, Minnesota, Nebraska, Nevada, New York
2022-09-26
Active, closed
A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer
NCT05483868Non-muscle-invasive Bladder Cancer, NMIBC, Non-Muscle Invasive Bladder Carcinoma, Non-Muscle Invasive Bladder Neoplasms
Aura Biosciences
Phase 1
55
Arkansas, California, Colorado, New York, Pennsylvania, South Carolina, Tennessee, Texas
2022-09-26
Active, closed
Study of Axicabtagene Ciloleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Follicular Lymphoma
NCT05371093Relapsed/Refractory Follicular Lymphoma
Kite, A Gilead Company
Phase 3
231
California, Florida, Kansas, Maryland, Massachusetts, North Carolina, Pennsylvania, Tennessee
2022-09-22
Active, closed
Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Cutaneous Squamous Cell Carcinoma
NCT05323253Recurrent Squamous Cell Carcinoma
Alpha Tau Medical LTD.
Not applicable
86
Arizona, California, Florida, Georgia, Minnesota, New Jersey, New Mexico, New York
2022-09-21
Active, closed
CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma
NCT05440786Sarcoma, Ewing, Neoplasm Metastasis
Eli Lilly and Company
Phase 2
46
Arizona, California, Indiana, Missouri, Rhode Island
2022-09-20
Recruiting
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
NCT05519085Relapsed or Refractory Multiple Myeloma
Celgene
Phase 3
810
California, Colorado, Connecticut, Florida, Georgia, Kansas, Louisiana, Maryland
2022-09-20
Active, closed
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma
NCT05409066Follicular Lymphoma (FL)
Genmab
Phase 3
549
Arizona, Arkansas, California, Georgia, Hawaii, Illinois, Indiana, Louisiana
2022-09-20
Active, closed
Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors
NCT05462717Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Pancreatic Ductal Adenocarcinoma, Advanced Solid Tumor
Revolution Medicines, Inc.
Phase 1
222
Arkansas, California, Florida, Maryland, Massachusetts, New York, Tennessee, Texas
2022-09-19
Active, closed
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT05242484Colitis, Ulcerative
Janssen Research & Development, LLC
Phase 2
577
California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Idaho, Indiana
2022-09-19
Active, closed
The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)
NCT05540327Systemic Lupus Erythematosus
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Phase 2
379
California, Florida, Indiana, Michigan, Minnesota, Ohio, Tennessee
2022-09-16
Active, closed
Phase 2a to Evaluate PL-8177 in Subjects with Active Ulcerative Colitis (UC)
NCT05466890Ulcerative Colitis, Ulcerative Colitis Acute, Ulcerative, Ulcerative Colitis Flare
Palatin Technologies, Inc
Phase 2
16
Arizona, California, Florida, Kansas, Louisiana, New Jersey, New York, Pennsylvania
2022-09-15
Recruiting
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
NCT05519449Prostate Cancer, Metastatic Castration-resistant Prostate Cancer, Castration Resistant Prostatic Cancer
Janux Therapeutics
Phase 1
272
Alabama, Arizona, California, Connecticut, Florida, Illinois, Maryland, Minnesota
2022-09-15
Active, closed
A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy
NCT05450692Advanced or Metastatic Non-Small Cell Lung Cancer
AstraZeneca
Phase 3
594
Alabama, Arizona, California, Florida, Georgia, Indiana, Maryland, Mississippi
2022-09-15
Active, closed
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
NCT05531565Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus
Biogen
Phase 2/3
450
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2022-09-13
Active, closed
A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis
NCT05528510Colitis, Ulcerative
Janssen Research & Development, LLC
Phase 3
418
Arizona, California, Colorado, Florida, Georgia, Kansas, Michigan, New York
2022-09-13
Active, closed
A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
NCT05057494Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
AstraZeneca
Phase 3
607
Arizona, California, Colorado, Florida, Massachusetts, Minnesota, Missouri, New York
2022-09-12
Recruiting
Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)
NCT05308264Low Risk Myelodysplastic Syndromes
Rigel Pharmaceuticals
Phase 1/2
86
California, Florida, Missouri, New Jersey, New York, North Carolina, Ohio, Texas
2022-09-12
Recruiting
AngelMed Guardianยฎ System PMA Post Approval Study
NCT05412927Acute Coronary Syndrome
Angel Medical Systems
Observational
500
Arizona, California, Florida, Georgia, Louisiana, Michigan, Oklahoma, Texas
2022-09-07
Active, closed
Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal Cancer
NCT05425940Colorectal Cancer
Exelixis
Phase 3
901
Alabama, Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana
2022-09-07
Recruiting
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
NCT05489211Endometrial Cancer, Gastric Cancer, Metastatic Castration-resistant Prostate Cancer, Ovarian Cancer
AstraZeneca
Phase 2
454
California, Indiana, Kansas, Massachusetts, Michigan, New Jersey, New Mexico, New York
2022-09-06
By invitation
Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease
NCT04905693Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease, Progressive Pulmonary Fibrosis
United Therapeutics
Phase 3
1,850
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2022-09-06
Recruiting
Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial
NCT05334368Hypereosinophilic Syndrome
GlaxoSmithKline
Phase 3
109
California, Georgia, Massachusetts, Michigan, Minnesota, New York, Ohio, South Carolina
2022-09-06
Active, closed
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1
NCT05481879Myotonic Dystrophy Type 1 (DM1)
Dyne Therapeutics
Phase 1/2
127
California, Florida, Indiana, Iowa, Missouri, New York, Texas, Virginia
2022-09-05
Recruiting
TVMR With the INNOVALVE System Trial - Early Feasibility Study
NCT04919980Mitral Valve Regurgitation (Degenerative or Functional)
Edwards Lifesciences
Not applicable
85
California, Florida, Georgia, Illinois, Michigan, Minnesota, Missouri, New Jersey
2022-09-01
Recruiting
Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer
NCT05168566Non-small Cell Lung Cancer
Teligene US
Phase 2
99
California, Georgia, Kentucky, Maryland, North Carolina, Texas
2022-09-01
Active, closed
A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab
NCT05378425Cancer, Tumor, Solid, Advanced Solid Tumor, Metastatic Cancer
Nectin Therapeutics Ltd
Phase 1
90
California, Louisiana, Texas
2022-09-01
Recruiting
Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
NCT05533697Advanced Solid Tumors
ModernaTX, Inc.
Phase 1/2
361
California, Colorado, District of Columbia, Florida, Illinois, Massachusetts, Michigan, Missouri
2022-09-01
Recruiting
Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.
NCT05422911Metastatic Cancer, Neoplasm, Prostate, Castrate-sensitive, Castrate-sensitive Prostate Cancer
Sun Pharmaceutical Industries Limited
Phase 2
192
California, Florida, Michigan, Missouri, New York, North Carolina, Oregon, Pennsylvania
2022-08-31
Recruiting
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
NCT05386108Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms
Stemline Therapeutics, Inc.
Phase 1/2
73
California, Illinois, Massachusetts, Michigan, Ohio, Oregon, Tennessee, Texas
2022-08-31
Active, closed
Safety, Tolerability and PK of Subcutaneous D-4517.2 in Subjects With Wet AMD or DME
NCT05387837Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Ashvattha Therapeutics, Inc.
Phase 2
50
California, Illinois, Indiana, Maryland, Massachusetts, Missouri, New Jersey, Pennsylvania
2022-08-31
Recruiting
Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)
NCT05281471Platinum-resistant Ovarian Cancer, Platinum-refractory Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
Genelux Corporation
Phase 3
186
Alabama, Arizona, California, Florida, Georgia, Indiana, Maryland, Michigan
2022-08-31
Active, closed
Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer
NCT05508906Metastatic Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, Breast Cancer
Olema Pharmaceuticals, Inc.
Phase 1
190
Arizona, California, Colorado, Florida, Iowa, Massachusetts, Michigan, Minnesota
2022-08-31
Recruiting
Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors
NCT05394103Advanced Cancer, Metastatic Cancer
Qurient Co., Ltd.
Phase 1/2
130
Arizona, California, Florida, Illinois, Minnesota, New Jersey, Texas
2022-08-30
Active, closed
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
NCT05271409Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)
Hoffmann-La Roche
Phase 3
132
Alabama, California, Colorado, District of Columbia, Florida, Maryland, Massachusetts, Michigan
2022-08-30
Recruiting
A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma
NCT05548296Endometrial Adenocarcinoma
Acrivon Therapeutics
Phase 2
350
Alabama, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Florida
2022-08-29
Active, closed
Development of a Self-collection Device for Cervical Cancer Screening
NCT05669911Human Papilloma Virus Infection Type 16, Human Papilloma Virus Infection Type 18, Human Papilloma Virus
Teal Health, Inc.
Not applicable
235
California, Colorado, Louisiana, Massachusetts, Texas, Wisconsin
2022-08-28
Active, closed
A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)
NCT05500222NASH, Cirrhosis, Liver
Madrigal Pharmaceuticals, Inc.
Phase 3
845
Alabama, Arizona, Arkansas, California, Colorado, Florida, Georgia, Illinois
2022-08-26
Recruiting
Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer
NCT05455619HR+/HER2-negative Breast Cancer, Metastatic Breast Cancer
SynDevRx, Inc.
Phase 1/2
52
California, Florida, Illinois, Michigan, Ohio, Pennsylvania, Tennessee, Texas
2022-08-26
Recruiting
A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery
NCT05156983Coagulation Disorder
Takeda
Phase 3
440
Arkansas, California, Colorado, Florida, New Jersey, North Carolina, Ohio, Oklahoma
2022-08-24
Active, closed
Gene Therapy for Cardiomyopathy Associated With Friedreich's Ataxia
NCT05445323Friedreich Ataxia, Cardiomyopathy, Secondary
Lexeo Therapeutics
Phase 1/2
8
California, Florida, Minnesota
2022-08-24
Active, closed
A Study to Learn About the Safety of Diranersen (BIIB080) Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age
NCT05399888Mild Cognitive Impairment Due to Alzheimer's Disease, Alzheimer's Disease Dementia
Biogen
Phase 2
416
Arizona, California, Colorado, Florida, Hawaii, Massachusetts, New York, North Carolina
2022-08-24
Active, closed
First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC)
NCT05361395Extensive Stage Small Cell Lung Cancer
Amgen
Phase 1
184
California, Delaware, Michigan, New Jersey, New York, North Carolina, South Dakota, Washington
2022-08-24
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 24 September 2026. https://priyalifescience.com/clinical-trials-usa/state/california?page=38

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,115 studies in total at the last sync on 24 Sep 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 5,299 of those studies with a site in California.

How many clinical trials are recruiting in California?

2,762 of the 5,299 studies on this page are recruiting new participants as of the 24 Sep 2026, 03:16 UTC sync. A further 162 have not yet opened recruitment, 2,207 are active but closed to new participants, and 168 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.