First in Human Clinical Investigation of the FIRE1 System in Heart Failure Patients (FUTURE-HF)

Main Inclusion Criteria * Adults 18 years or older with heart failure with any of the following in the past 6 months: a decompensation due to heart failure resulting in a heart failure hospitalisation, heart failure treatment in a hospital day-care setting or urgent outpatient heart failure visit * Receiving treatment in accordance with internationally recognised guidelines. * Signed patient informed consent form Main Exclusion Criteria: * Significant comorbidity that would interfere with the ability to safely complete the clinical investigation protocol * Patients with an estimated Glomerular Filtration Rate (eGFR) \< 30 ml/min * Patients with IVC filter placement in situ, abnormal IVC or femoral venous anatomy or known congenital malformation or absence of IVC or occlusive or free-floating thrombus in the IVC * Patients with implantable ventricular assist device (LVAD, RVAD, BiVAD) in situ * Patients with Cardiovascular Implantable Electronic Device (CIED) implanted ≤ 3 months prior to enrolment * Patients with conditions associated with occlusion of the IVC, iliac or common femoral veins (e.g. venous leg ulcers)