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Clinical Trials in the UK / NCT01838512
Active, not recruiting Observational

Prospective Research Assessment in Multiple Myeloma: An Observational Evaluation (PREAMBLE)

NCT01838512 · tracked via the Priya Life Science UK tracker
Sponsor
Bristol-Myers Squibb
Phase
Observational
Started
2012-06-13
Last updated
2025-12-02

Condition(s) studied

Multiple Myeloma

Study summary

The purpose of this study is to assess the clinical effectiveness of all approved multiple myeloma (MM) therapies in the newly-diagnosed (NDMM) and the relapsed/refractory MM (RRMM) settings in real-world clinical practice.

Eligibility

Sex
ALL
Min age
18 Years
Max age
Healthy volunteers
No
For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: For RRMM participants who have received at least one prior line of therapy (LoT) for MM: * Have documented progression from a prior LoT * Participants who have initiated treatment with one of the following therapies within 90 days before consent for this study OR in the case where treatment has not yet been initiated, documentation that the treatment strategy was determined before consent for this study must be provided, and treatment must be initiated within 30 days after consent: * IMiDs * PIs * Combination of IMiD + PI * Newer agents with novel MOAs alone or in combination (eg, mAbs, HDACIs, Akt inhibitors, SINE, or CAR T-cell therapies) For NDMM participants receiving frontline therapy: * Eligible to receive frontline therapy for MM (no prior MM treatment) * Participants who have initiated treatment for MM with one of the following therapies within 90 days before consent for this study OR in the case where treatment has not yet been initiated, documentation that the treatment strategy was determined before consent for this study must be provided, and treatment must be initiated within 30 days after consent: * IMiDs * PIs * Combination of IMiD + PI * Newer agents with novel MOAs alone or in combination (eg, mAbs, HDACIs, Akt inhibitors, SINE, or CAR T-cell therapies) Exclusion Criteria: * Participants who are currently participating in a clinical trial for MM * Participants who are currently receiving treatment for primary cancer other than MM * Participants who are not willing or able to provide informed consent * Participants who are incarcerated * Participants under compulsory detention for treatment of a physical (eg, infectious) or psychiatric illness Other protocol-defined inclusion/exclusion criteria apply

Primary outcome measure(s)

Trial sites (130)

FacilityCityRegionStatus
Local Institution Birmingham Alabama
Local Institute Goodyear Arizona
Local Institution - 0023 Anaheim California
Local Institution Anaheim California
Local Institution - 0045 Burbank California
Local Institution Corona California
Local Institution - 0048 Downey California
Local Institution - 0052 Fountain Valley California
Local Institute Los Angeles California
Local Institute Santa Rosa California
Local Institution - 0051 Santa Rosa California
Local Institution Brooksville Florida
Local Institution - 0044 Fort Lauderdale Florida
Local Institution Jacksonville Florida
Local Institute Valdosta Georgia
Local Institution - 0047 Valdosta Georgia
Local Institution Skokie Illinois
Local Institution - 0041 Springfield Illinois
Local Institution - 0058 Anderson Indiana
Local Institution - 0011 Indianapolis Indiana
Local Institution Indianapolis Indiana
Local Institute Sioux City Iowa
Local Institute Louisville Kentucky
Local Institution - 0042 Louisville Kentucky
Local Institution Lafayette Louisiana
Local Institution Shreveport Louisiana
Local Institution Minneapolis Minnesota
Local Institution - 0030 Woodbury Minnesota
Local Institute Southaven Mississippi
Local Institute Kansas City Missouri
Local Institution - 0050 Kansas City Missouri
Local Institution - 0037 Missoula Missouri
Local Institute Saint Joseph Missouri
Local Institution - 0020 Springfield Missouri
Local Institution Springfield Missouri
Local Institution St Louis Missouri
Local Institute Missoula Montana
Local Institute Missoula Montana
Local Institute Omaha Nebraska
Local Institution - 0024 Omaha Nebraska

+ 90 more sites — see the full list on the official registry below.

More Bristol-Myers Squibb trials in the UK

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT01838512 on ClinicalTrials.gov ↗ ← All trials in the UK