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Updated 12 Aug 2026 · ClinicalTrials.gov

Sickle Cell Disease Trials in the UK

← All UK trials

The most recently updated industry-sponsored clinical trials recruiting across the United Kingdom — searchable by condition, sponsor, phase and city. Refreshed daily from the ClinicalTrials.gov registry.

1

Recruiting now

3

Studies tracked

123

Cities with sites

Recruiting Phase 2

A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease

Sickle Cell Disease
Forma Therapeutics, Inc. · started 2023-01-12

📍 London · Manchester

NCT06198712 on ClinicalTrials.gov ↗

By invitation Phase 4

A Study to Provide Access to Mitapivat for Participants Who Previously Participated in an Agios-Sponsored Mitapivat Study

Pyruvate Kinase Deficiency, Anemia, Hemolytic, Sickle Cell Disease, Thalassemia
Agios Pharmaceuticals, Inc. · started 2023-07-06

📍 Manchester

NCT05777993 on ClinicalTrials.gov ↗

By invitation Phase 3

A Long-term Follow-up Study in Participants Who Received CTX001

Beta-Thalassemia, Thalassemia, Sickle Cell Disease, Hematologic Diseases
Vertex Pharmaceuticals Incorporated · started 2021-01-20

📍 London

NCT04208529 on ClinicalTrials.gov ↗

No trials match your search.

Browse by city

London · 118 Manchester · 32 Birmingham · 29 Glasgow · 29 Cambridge · 25 Oxford · 25 Leeds · 20 Bristol · 20 Sheffield · 19 Newcastle upon Tyne · 18 Cardiff · 16 Edinburgh · 11 Liverpool · 11 Sutton · 11 Salford · 10 Southampton · 10

Browse by condition

Advanced Solid Tumor · 4 Prostate Cancer · 4 Sickle Cell Disease · 3 Breast Cancer · 3 Urinary Urge Incontinence (UUI) · 2 Urinary Frequency (UF) · 2 Healthy Volunteers · 2 Multiple Sclerosis · 2 Alzheimer's Disease · 2 Ovarian Cancer · 2 Developmental and Epileptic Encep… · 2 Non-Small Cell Lung Cancer · 2 Myeloproliferative Neoplasms · 2 Endometrial Cancer · 2 Generalized Myasthenia Gravis · 2 Thalassemia · 2

Cite this page

Priya Life Science (2026). Clinical Trials in the UK Tracker. Available at: https://priyalifescience.com/clinical-trials-uk/condition/sickle-cell-disease (Accessed: 13 August 2026).

Embed this data ↗

Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one UK site, most recently updated first, refreshed daily. This is a curated slice of the registry, not every UK trial; UK studies may also be registered on ISRCTN. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our UK Pharma Salary Guide, or see our Ireland, EU and USA trackers.