ER+ HER2- Advanced Breast Cancer Clinical Trials in the UK

ER+ HER2- Advanced Breast Cancer Trials in the UK

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a UK site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full UK registry across all sponsors is far larger. UK studies may also be registered separately on ISRCTN.

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Recruitment status

Phase

Lead sponsor

Site city

All 5 cities

Target enrolment

Status

Study

Lead sponsor

Phase

Enrol

UK sites

Start

Recruiting

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors

NCT06188520ER+ HER2- Advanced Breast Cancer, High-grade Serous Ovarian Cancer (HGSOC)

AstraZeneca

Phase 1/2

564

Cambridge, Leeds, London, Manchester

2023-12-05

Active, closed

Study of AZD9833 Alone or in Combination in Women With Advanced Breast Cancer.

NCT03616587ER+ HER2- Advanced Breast Cancer

AstraZeneca

Phase 1

396

Cambridge, Leeds, London, Manchester, Sutton

2018-10-11

Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a UK investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 17 September 2026. https://priyalifescience.com/clinical-trials-uk/condition/er-her2-advanced-breast-cancer

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