A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score

Condition(s) studied

Study summary

Liberation from mechanical ventilation involves three steps: weaning, readiness assessment, and extubation. Readiness is determined using clinical criteria such as improvement of the underlying condition, hemodynamic stability, and adequate respiratory effort. Successful extubation is defined as not requiring invasive support within 48 hours. Due to the complexity of ICU patients, various clinical parameters and multi-component scores have been developed to predict extubation success. This study aims to develop and evaluate a multi-component score, the Readiness for EXtubation score (REXs), to predict extubation readiness in ICU patients under invasive mechanical ventilation.

Eligibility

Primary outcome measure(s)

• Extubation failure in 48 hours — From the beginning of the extubation process until 48 hours after extubation
  Extubation failure within 48 hours is defined as the need for reintubation or resumption of mechanical ventilation within two days after planned extubation, indicating the patient could not sustain spontaneous breathing independently.

Trial sites (7)

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