To Compare the Effects of Oxytocin and Carbetocin on Intraoperative Hemodynamic Changes in Cesarean Section Surgeries.

NCT06956365 · tracked via the Priya Life Science Turkey tracker

Sponsor

Yuzuncu Yil University

Phase

Not applicable

Started

2024-05-14

Last updated

2025-05-04

Condition(s) studied

Cesarean Section

Investigational drug(s) / intervention(s)

Group-CGroup-O

Group-C: 100 iu carbetosin administered to carbetocin group

Group-O: In cesarean surgery, 5 IU of oxytocin will be administered after the baby delivered.

Study summary

To compare the effects of oxytocin and carbetocin, used as uterotonics in elective caesarean section surgeries, in terms of intraoperative hemodynamic changes.

Eligibility

Sex

FEMALE

Min age

18 Years

Max age

40 Years

Healthy volunteers

Accepted

Inclusion Criteria: * Patients scheduled for caesarean sections * Between 18-40 years * ASA I-II group * Those who will undergo general anesthesia * Those between 35-40 weeks of pregnancy * 1st and 2nd caesarean sections Exclusion Criteria: * Those who prefer spinal or epidural anesthesia * Those who are outside the age range of 18-40 * Those who are ASA III and above * Those with HT, DM, cardiac and respiratory diseases * Preeclampsia, eclampsia, HELLP * Those with a history of drug use that affects the cardiovascular system * Placenta Previa, Placenta Acreta, Placenta Acreta

Primary outcome measure(s)

Uterine tonus — For 30 minutes after carbetocin administration.
The effect of carbetocin on uterine tone will be evaluated by the surgical team using a numerical scoring scale between 0-10. A score of 0 will indicate atony, and a score of 10 will indicate full contraction.
Additional uterotonic drug requirement — For 30 minutes after carbetocin administration.
If the uterine tone is 7 or below, the surgical team will perform uterine massage, and in patients who do not see a sufficient increase in uterine tone, an additional uterotonic, 0.2 mg methylergonavine (Methyl ampoule 0.2 mg/ml) will be administered IM by the anesthesia team and recorded.

Trial sites (1)

Facility	City	Region	Status
Van Yuzuncu Yil University	Van	Tuşba	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06956365 on ClinicalTrials.gov ↗ ← All trials in Turkey