Effect of Apical Third Enlargement to Different Taper and Master Apical Preparation Size on Periapical Healing and Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment

NCT07166679 · tracked via the Priya Life Science India tracker

Sponsor

Postgraduate Institute of Dental Sciences Rohtak

Phase

Not applicable

Started

2025-04-18

Last updated

2025-09-10

Condition(s) studied

Asymptomatic Irreversible Pulpitis

Investigational drug(s) / intervention(s)

root canal treatment with 2% taperroot canal treatment with 4% taperroot canal treatment with 6 %taper

root canal treatment with 2% taper: root canal treatment with 2%taper

root canal treatment with 4% taper: root canal treatment with 4 %taper

root canal treatment with 6 %taper: root canal treatment with 6 %taper

Study summary

To Determine Effect Of Apical Third enlargement To Different Taper And Master Apical Preparation Size On Periapical Healing And Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment : A Randomized Clinical Trial

Eligibility

Sex

ALL

Min age

18 Years

Max age

65 Years

Healthy volunteers

Accepted

Inclusion Criteria: 1. 18-65 years of age of either sex 2. Asymptomatic teeth having pulpal necrosis with apical periodontitis in a mandibular molar (no response to EPT or cold test) 3. Radiographic evidence of periapical radiolucency corresponding to a periapical index (PAI) score \>/=3 in mesial root of mandibular molars Exclusion Criteria: 1. Patients who were medically compromised 2. Patients with initial apical binding file (IABF) size more than 20 3. Pregnancy; lactation \& contraceptives. 4. Positive history of antibiotic use within the past month or required antibiotic premedication for dental treatment (including infective endocarditis or pros thetic joint prophylaxis -

Primary outcome measure(s)

periapical healing using the Periapical index score — 12 month follow up
Description: Periodical status will be assessed in periapical radiograph • Periapical status will be checked according to periapical index given by Orstavik * Scoring of periapical radiolucency of each tooth will be done according to the following 5 point scale (PAI score) * Score 1- Normal periapical structure * Score 2- Small changes in bone structure * Score 3- Changes in bone structure with some mineral loss * Score 4- Periodontitis with well-defined radiolucent area * Score 5- Severe periodontitis with exacerbating features Time Frame: 12MONTHS

Trial sites (1)

Facility	City	Region	Status
Pgids Rohtak	Rohtak	India	Recruiting