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Clinical Trials in Germany / NCT06595602
Recruiting Observational

Intelligent Lung Support in the Intensive Care Unit

NCT06595602 · tracked via the Priya Life Science Germany tracker
Phase
Observational
Started
2025-05-25
Last updated
2026-07-02

Condition(s) studied

Mechanical VentilationIntensive Care Medicine

Investigational drug(s) / intervention(s)

Artificial intelligence based decision support system (AI-DSS); software

Artificial intelligence based decision support system (AI-DSS); software: The device is intended for monitoring and recommending ventilator settings, ventilation mode to qualified Intensive Care Unit (ICU) health care professionals (HCP). This is for medical indications that require invasive mechanical ventilation of the respiratory system in the ICU under international / EU guidelines. The device receives clinical data via the ICU's data integration platform that includes patient physical and demographic data as well as current vital signs, ventilation parameters, blood gas analysis, general blood laboratory reports, fluid balance and medication. Prediction models based on artificial intelligence algorithms are used to deduce therapy suggestions from received data. The algorithm is carried out on a secured cloud platform.

Study summary

The aim of this observational study is to test the IntelliLung decision support system based on artificial intelligence. This system is intended to help to set the ventilator. The study includes patients with and without ARDS (acute respiratory distress syndrome) who are receiving invasive mechanical ventilation, as well as patients with additional extracorporeal lung support. The study will be conducted in several centers.

The main question of the study:

How well do the mechanical ventilation settings of healthcare staff match the recommendations of the IntelliLung system?

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: 1. Male and female patients, age ⪰18 years 2. Written informed consent 3. Invasively mechanically ventilated patients expected to be intubated for more than 24 hours. Exclusion Criteria: 1. Expected to die within ≤48 hours 2. Participation in an interventional mechanical ventilation trial 3. Mechanical Ventilation with a closed-loop ventilation mode 4. Persons dependent on the sponsor and/or investigator 5. Subjects who are currently imprisoned or otherwise in confinement ordered by law or other official authorities

Primary outcome measure(s)

Trial sites (5)

FacilityCityRegionStatus
Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany Dresden Germany Recruiting
Dipartimento di Scienze Chirurgiche e Diagnostiche Integrate, University of Genoa, Genoa, Italy Genova Italy Not Yet Recruiting
Department of Anaesthesiology and Intensive Care, National Medical Institute of the Ministry of Interior and Administration, Warsaw, Poland Warsaw Poland Recruiting
Department of Intensive Care Medicine. Hospital Universitario de La Princesa. Universidad Autonoma de Madrid, Madrid, Spain Madrid Spain Not Yet Recruiting
Critical Care Department, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA), Sabadell, Spain Sabadell Spain Recruiting

More Technische Universität Dresden trials in Germany

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06595602 on ClinicalTrials.gov ↗ ← All trials in Germany