Patients undergoing cystectomy for either oncological or non-oncological indications are prospectively enrolled following informed consent. This study design incorporates a comprehensive medical history, detailed prospective documentation of clinicopathological parameters, and serial measurements of infectious markers pre- and post-operatively. In-hospital complications are meticulously recorded, and long-term outcomes assessed through structured follow-up interviews at 3, 6, and 12 months. These follow-ups utilize standardized questionnaires to evaluate post-discharge infectious complications and gather patients' perspectives on their in-hospital experiences, providing a robust understanding of both clinical outcomes and patient-reported experiences.
Eligibility
Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Disease which requires removal of the urinary bladder
Exclusion Criteria:
* Patient does not want to participate
Primary outcome measure(s)
Infectious parameters on the first postoperative day after cystectomy — First postoperative day IL-6 level, procalcitonin level and wound drainage culture
Postoperative fever — Surgery - discharge Proportion of cystectomy patients that develops fever postoperatively (≥38.0°C)
Antibiotic use — Surgery - discharge Proportion of cystectomy patients that need additional oral or i.v. antibiotic therapy (on top of the hospital standard)
In-hospital complications — Surgery - discharge Clavien-Dindo Classification and Comprehensive Complication Index
Antibiotic therapy within the first year after discharge — 0-12 months after discharge Proportion of cystectomy patients that needs antibiotic therapy associated with urinary diversion in the first year after discharge
Fever within the first year after discharge — 0-12 months after discharge Proportion of cystectomy patients with urinary tract associated fever in the first year after discharge
Emergency consultation — 0-12 months after discharge Proportion of cystectomy patients with a cystectomy-associated emergency consultation in the first year after discharge
Inpatient admission — 0-12 months after discharge Proportion of cystectomy patients with a cystectomy-associated inpatient admission in the first year after discharge
Preoperative interleukin-6 level — 1 day before surgery IL-6 level before surgery
Trial sites (1)
Facility
City
Region
Status
Urology Department - LMU Klinikum
Munich
Outside U.S./Canada
Recruiting
More Ludwig-Maximilians - University of Munich trials in Germany
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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