PREG - Offspring: Investigation of Children From Mothers With and Without Gestational Diabetes

Condition(s) studied

Investigational drug(s) / intervention(s)

intrauterine exposure to elevated glucose levels: intrauterine exposure to elevated glucose levels

Study summary

Gestational diabetes is the most common complication during pregrancy. With a screening between week 24 and 28 of gestation women with gestational diabetes can be identified and treated. Treatment comprises modification of diet and in some cases taking medication. This treatment lowers undesirable events like macrosomia or premature birth. However, unitl gestational diabetes is diagnosed the fetus is exposed to increased intrauterine glucose levels. The long-term effects of a well-managed gestational diabetes on the development of the offspring is still not well understood. Therefore, the PREG - Offspring study investigates several aspects of development in children from healthy and gestational diabetes mothers until adulthood.

Eligibility

Primary outcome measure(s)

• Body height — Change in body height from birth to age 6, 10, 14 and 17
  Body height is measured with a tape measure in centimeter (cm)

Trial sites (1)

More University Hospital Tuebingen trials in Germany