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Trackers› Clinical trials› Advanced Solid Tumors
Clinical trial register · European Union · CTIS

Advanced Solid Tumors Clinical Trials in the EU, 2026

The most recently authorised trials on the EU Clinical Trials Information System (CTIS), the single register for every trial run under the EU Clinical Trials Regulation (536/2014). CTIS holds a far larger historical archive than any one list can usefully show โ€” this register states both numbers rather than picking one.

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Source: EMA Clinical Trials Information System (CTIS). Showing the 2500 most recently authorised of 12490 total CTIS records โ€” a stated recency window, not the full historical archive. Synced 25 Sep 2026, 03:16 UTC
2500
Shown in this register
most recently authorised
12,490
Total on CTIS
full historical archive
741
Phase III
within the shown window
Top member states
Spain 1016 France 881 Germany 860 Italy 735 Poland 585 Netherlands 531
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Trials for Advanced Solid Tumors

22 of 2500 shown studies
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Phase
Study
Lead sponsor
Area
Member states
Decision
Phase I
[14C]Navlimetostat Mass Balance Study in Healthy Female Participants
2026-527504-24-00Advanced Solid Tumors
Bristol-Myers Squibb Services Unlimited Company
Neoplasms
Netherlands
24/09/2026
Phase I
A Study of RO7806767 as Single Agent and in Combination with Pembrolizumab in Participants with Advanced Solid Tumors
2026-525215-13-00Advanced Solid Tumors
F. Hoffmann-La Roche AG
Neoplasms
Spain, Poland, Romania, Hungary, Germany, Italy, Belgium, Netherlands, Denmark, France
07/09/2026
Phase I
Phase 1 Study of PF-08046033 in Advanced Solid Tumors
2025-522532-14-00Advanced solid tumors
Pfizer Inc.
Neoplasms
Netherlands, France, Spain
11/08/2026
Phase I
First-in-Human Trial of DS3610a in Participants with Advanced Solid Tumors
2025-521173-13-00Advanced Solid Tumors
Daiichi Sankyo Inc.
Neoplasms
France, Spain
08/05/2026
Phase I/II
Phase 1/2A Study of OTP-01, a Dual Paratopic PD-1/VEGFR2 Antibody, in Patients with Advanced Solid Tumors
2025-524111-37-00advanced solid tumors
Ottimo Pharma Limited
Neoplasms
Ireland, Spain, Portugal
14/04/2026
Phase I/II
A Phase Ib/II, Multicenter, Open-Label Study to Evaluate Safety, Efficacy, and Pharmacokinetics of YL201 in Combination with Other Anti-Cancer Therapies in Patients with Advanced Solid Tumors
2025-523742-27-00Advanced solid tumors
Medilink Therapeutics (Suzhou) Co. Ltd.
Neoplasms
Poland, Spain, France, Romania, Italy, Belgium, Hungary, Germany
17/03/2026
Phase I
A Study of PHN-012 in Patients With Advanced Solid Tumors
2025-523756-31-00Advanced Solid Tumors
Pheon Therapeutics Limited
Neoplasms
Spain
06/03/2026
Phase I
Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors
2025-523232-39-00Advanced Solid Tumors
Merck Healthcare KGaA
Neoplasms
Spain
03/03/2026
Phase I
A Phase 1 Study for ZW251 in Participants with Solid Tumors.
2025-523088-39-00Advanced Solid Tumors
Zymeworks Bc Inc.
Neoplasms
Portugal, Ireland, Spain
15/01/2026
Phase I
C5951001- A Phase 1 Study of PF-08046876 in Participants with Advanced Solid Tumors.
2025-521729-33-00advanced solid tumors
Pfizer Inc.
Neoplasms
Spain
23/12/2025
Phase I
Study of GS-5319 in Adults With Solid Tumors
2025-522397-36-00Advanced solid tumors
Gilead Sciences Inc.
Neoplasms
Spain
24/11/2025
Phase I
A Phase 1 Study of JNJ-89862175, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 3 Antibody Drug Conjugate, for Advanced Solid Tumors.
2025-521407-52-00Advanced Solid Tumors
Janssen Cilag International
Neoplasms
France
21/11/2025
Phase I/II
Phase 1/2 Study of PYX-201 in Combination with Pembrolizumab in Advanced Solid Tumors
2025-521828-30-00Advanced Solid Tumors
Pyxis Oncology Inc.
Neoplasms
France, Spain, Poland
19/11/2025
Phase I/II
A Phase 1/2a, First-in-human, Open label Study of BMS-986517 as Monotherapy in Adult Participants with Advanced Solid Tumors
2025-522203-23-00Advanced Solid Tumors
Bristol-Myers Squibb Services Unlimited Company
Neoplasms
Denmark, Spain
07/11/2025
Phase I
A Study Testing the Investigational Drug XmAb541 in people with Advanced Cancer
2025-521981-90-00Advanced Solid Tumors
Xencor Inc.
Neoplasms
Spain, France, Belgium, Denmark
27/10/2025
Phase I
A Phase 1 Study of NDI-219216 in Patients with Advanced Solid Tumors with and without Microsatellite Instability and/or Deficient Mismatch Repair
2025-522774-36-00Advanced solid tumors
Nimbus Wadjet Inc.
Neoplasms
Spain, Portugal, France, Ireland
15/09/2025
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Cite this view

Priya Life Science (2026). EU Clinical Trials Register (CTIS), filtered. Derived from the EMA Clinical Trials Information System. Retrieved 25 September 2026. https://priyalifescience.com/clinical-trials-europe/condition/advanced-solid-tumors

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About this register

This register is built from the EU Clinical Trials Information System (CTIS), run by the European Medicines Agency: the single register for every trial authorised under the EU Clinical Trials Regulation (536/2014). CTIS held 12,490 trial records at the last sync on 25 Sep 2026, 03:16 UTC; this register shows the 2,500 most recently authorised of them, a stated recency window rather than the full archive. The list can be downloaded as CSV or JSON.

This page shows the 22 of those trials with a site in Advanced Solid Tumors.

How many recently authorised EU trials have a site in Advanced Solid Tumors?

22 of the 2,500 most recently authorised trials in this register list a site in Advanced Solid Tumors; 0 of them are Phase III. Trials are counted by authorisation on CTIS, not by recruitment status, which CTIS does not publish in the same form as ClinicalTrials.gov.

Summary by phase

Trials by phase (Advanced Solid Tumors), 22 trials
PhaseTrialsShare
Phase I1568.2%
Phase I/II731.8%

Most active sponsors

Lead sponsors with the most trials (Advanced Solid Tumors)
Lead sponsorTrials
Pfizer Inc.3
Bristol-Myers Squibb Services Unlimited Company2
AstraZeneca AB1
BeOne Medicines I GmbH1
BioNTech SE1
Daiichi Sankyo Inc.1
Eikon Therapeutics Inc.1
F. Hoffmann-La Roche AG1
Gilead Sciences Inc.1
Janssen Cilag International1
Listing here is informational and not medical advice; eligibility is determined by each study team. Looking for Irish sites? See the Ireland, UK or USA registers. For approved medicines, see the EMA Approvals Tracker.