Ultrasound Biomicroscopy: Ultrasound biomicroscopy is performed as a non-invasive diagnostic imaging procedure to evaluate postoperative anterior segment anatomy, including intrascleral lake characteristics and filtering bleb morphology, in patients with primary open-angle glaucoma following combined deep sclerectomy with trabeculotomy.
Study summary
Primary open-angle glaucoma is a chronic optic neuropathy that often requires surgical intervention when medical treatment fails. Deep sclerectomy is a non-penetrating glaucoma surgery that aims to reduce intraocular pressure while minimizing complications. When combined with trabeculotomy, additional aqueous outflow may be achieved.
Ultrasound biomicroscopy (UBM) allows detailed imaging of the anterior segment and provides valuable information about postoperative anatomical changes that cannot be assessed clinically. This observational study aims to evaluate UBM findings after combined deep sclerectomy with trabeculotomy in patients with primary open-angle glaucoma and to correlate these findings with clinical outcomes.
Eligibility
Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Diagnosis of primary open-angle glaucoma (POAG), including juvenile open-angle glaucoma (JOAG).
* Patients who underwent combined deep sclerectomy with trabeculotomy.
* Clear media allowing adequate ultrasound biomicroscopy imaging.
* Written informed consent obtained from the patient .
Exclusion Criteria:
* Secondary glaucomas (e.g., neovascular, uveitic, traumatic, or angle-closure glaucoma).
* Previous glaucoma filtering surgery in the studied eye.
* Coexisting ocular pathology affecting UBM assessment (e.g., severe corneal opacity, scleral pathology).
Primary outcome measure(s)
Intrascleral lake area on ultrasound biomicroscopy (UBM) — 3 and 6 months postoperatively Quantitative measurement of intrascleral lake area (mm²) using ultrasound biomicroscopy after combined deep sclerectomy with trabeculotomy.
Intrascleral lake height on ultrasound biomicroscopy (UBM) — 3 and 6 months postoperatively Quantitative measurement of intrascleral lake height (mm) using ultrasound biomicroscopy after combined deep sclerectomy with trabeculotomy.
Filtering bleb height on ultrasound biomicroscopy (UBM) — 3 and 6 months postoperatively Quantitative measurement of filtering bleb height (mm) using ultrasound biomicroscopy after combined deep sclerectomy with trabeculotomy.
Filtering bleb internal reflectivity on ultrasound biomicroscopy (UBM) — 3 and 6 months postoperatively Semi-quantitative assessment of filtering bleb internal reflectivity on ultrasound biomicroscopy after combined deep sclerectomy with trabeculotomy.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.