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Trackers› Clinical trials› Major Depressive Disorder (MDD)
Clinical trial register · China

Major Depressive Disorder (MDD) Trials in China, 2026

Every study on the ClinicalTrials.gov registry that lists a site in China and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 19052 matching records held by the registry are in this view. Synced 22 Sep 2026, 11:10 UTC
19052
Studies in scope
all four open statuses
11786
Recruiting now
open to new participants
2009
Lead sponsors
across recruiting studies
Top sites
Beijing 5 Shanghai 5 Chongqing 3 Changsha 2 Nanjing 2
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Recruitment status
Phase
Site location
Beijing5 Shanghai5 Chongqing3 Changsha2 Nanjing2
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Major Depressive Disorder (MDD) trials in China

18 of 19052 studies
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Status
Study
Lead sponsor
Phase
Enrol
Chinese sites
Start
Not yet open
iMORE+ Study: A Multi-Omics Cohort Study of Major Depressive Disorder
NCT07735143Major Depressive Disorder (MDD)
Shanghai Mental Health Center
Observational
150
Shanghai
2027-09-01
Not yet open
Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applications
NCT07444463Schizophrenia, Bipolar Disorder, Major Depressive Disorder (MDD)
Central South University
Not applicable
400
Changsha
2027-01-01
Not yet open
Amygdala-Targeted Transcranial Temporal Interference Stimulation for Major Depressive Disorder: A Randomized Sham-Controlled Trial of Clinical Efficacy and Neurobiological Mechanisms
NCT07829575Major Depressive Disorder (MDD
Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University
Not applicable
60
Shanghai
2026-10-20
Recruiting
Sertraline Combined With Multi-Strain Probiotics for Adolescent Depression
NCT07645157Major Depressive Disorder (MDD), Probiotic Intervention
First Affiliated Hospital of Chongqing Medical University
Phase 2
120
Chongqing
2026-10-01
Not yet open
Context-Guided Personalized iTBS for Depression
NCT07743398Major Depressive Disorder (MDD)
Capital Medical University
Not applicable
60
Beijing
2026-09
Not yet open
Probiotic IBNI617 for Moderate to Severe Depression
NCT07728253Major Depressive Disorder (MDD), IBNI617
IBIOME BIOTECHNOLOGY CO., LTD
Not applicable
148
Shanghai
2026-08
Recruiting
Efficacy and Safety of Sertraline Combined With Lactobacillus Crispatus in Adolescents With Depression
NCT07539805Major Depressive Disorder (MDD), Probiotic Intervention
First Affiliated Hospital of Chongqing Medical University
Phase 2
60
Longgang, Chongqing
2026-06-11
Not yet open
Efficacy and Safety of Transcranial Temporal Interference Stimulation for Depression
NCT07612501Major Depressive Disorder (MDD)
Yonggui Yuan
Not applicable
60
Nanjing
2026-05-30
Recruiting
Identification and Molecular Characterisation of Urban-environmental Stress Patterns Affecting Mental Illness
NCT07571226Major Depressive Disorder (MDD), Anxiety Disorder, Alcohol Use Disorder (AUD)
Huashan Hospital
Observational
680
Beijing, Shanghai
2026-04-10
Recruiting
Efficacy of Bright Light Therapy on Cognitive Impairment in Major Depressive Disorder and Its Neuroimaging Mechanisms: Protocol for a Randomised Controlled Trial
NCT07508215Major Depressive Disorder (MDD), Neuroimaging, Bright Light Treatment, Cognitive Impairment
Peking University Sixth Hospital
Not applicable
120
Beijing, Yanan
2026-04-10
Recruiting
Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment Outcomes of Severe Mental Disorders
NCT07479758Major Depressive Disorder (MDD), Schizophrenia, Bipolar Disorder, Severe Mental Disorders
Second Affiliated Hospital, Zhejiang University, School of Medicine
Observational
320
Hangzhou
2025-11-01
Not yet open
Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression๏ผˆSMART-I)
NCT07011693Major Depressive Disorder (MDD)
Xinyu Zhou
Phase 4
400
Chongqing
2025-06-20
Active, closed
Neurobiological Mechanisms of Pathological Rumination and Effects of Aripiprazole
NCT06937476Major Depressive Disorder (MDD), Rumination
Central South University
Not applicable
108
Changsha
2025-05-08
Recruiting
A Trial of Dextromethorphan and Bupropion Sustained-Release Tablets in Patients With Major Depressive Disorder
NCT06958692Major Depressive Disorder (MDD)
CSPC Ouyi Pharmaceutical Co., Ltd.
Phase 3
388
Beijing
2025-04-11
Recruiting
Multimodal Phenotyping in Adolescent Inpatient Depression: An Observational Study
NCT07247344Adolescent, Major Depressive Disorder (MDD, Bipolar Disorder (BD)
Jiangsu Province Nanjing Brain Hospital
Observational
1,000
Nanjing
2025-03-01
Recruiting
Assessment of the Efficacy and Safety of Fecal Microbiota Transplantation (FMT) in Patients With Major Depressive Disorder
NCT06692361Major Depressive Disorder (MDD), Depression - Major Depressive Disorder
Gang Wang
Not applicable
214
Wuhu, Beijing, Guangzhou, Shijiazhuang, Jining, Chengdu, Tianjin, Dali
2025-01-01
Recruiting
Effectiveness of MST Versus ECT for Major Depressive Episode
NCT06409325Major Depressive Disorder (MDD)
Shanghai Mental Health Center
Not applicable
210
Shanghai
2024-08-01
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Chinese investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 26 September 2026. https://priyalifescience.com/clinical-trials-china/condition/major-depressive-disorder-mdd

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in China and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 19,052 studies in total at the last sync on 22 Sep 2026, 11:10 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 18 of those studies listing the condition Major Depressive Disorder (MDD).

How many Major Depressive Disorder (MDD) trials are recruiting in China?

10 of the 18 studies on this page are recruiting new participants as of the 22 Sep 2026, 11:10 UTC sync. A further 7 have not yet opened recruitment, 1 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Major Depressive Disorder (MDD)), 18 studies
PhaseStudiesRecruitingShare
Not applicable10455.6%
Observational4322.2%
Phase 22211.1%
Phase 3115.6%
Phase 4105.6%

Most active sponsors

Lead sponsors with the most studies (Major Depressive Disorder (MDD))
Lead sponsorStudiesRecruiting
Central South University20
First Affiliated Hospital of Chongqing Medical University22
Shanghai Mental Health Center21
Capital Medical University10
CSPC Ouyi Pharmaceutical Co., Ltd.11
Gang Wang11
Huashan Hospital11
IBIOME BIOTECHNOLOGY CO., LTD10
Jiangsu Province Nanjing Brain Hospital11
Peking University Sixth Hospital11
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and India registers.