Bone Cancer Surgery Prospective Database

Condition(s) studied

Investigational drug(s) / intervention(s)

Bone cancer surgery: patients receive surgery based on the doctor's discretion and the consideration of the patients and their family

Study summary

According to the Global Burden of Disease Report, the number of cancer patients worldwide is increasing year by year. In 2023, there were a total of 18.5 million newly confirmed cases of malignant tumors worldwide, and it is expected to grow to 30.5 million cases by 2050. Among them, the number of new cases of malignant tumors of bone and articular cartilage increased by 86.4% from 1990 to 2023. Meanwhile, bone is a particularly common site for tumor metastasis, and almost half of cancer patients are at risk of developing bone metastasis. Surgical resection is the main treatment method for both primary and secondary bone cancer. For patients with bone cancer, the main goal of surgical treatment is to maintain the patient's function and mobility by relieving pain, preventing impending fractures and/or nerve compression, or stabilizing pathological fractures. Surgery for bone cancer often requires extensive exploration, osteotomy, and prosthetic reconstruction, resulting in significant surgical trauma. The incidence of postoperative complications remains high. The occurrence of postoperative complications can increase patient pain, prolong hospitalization time, increase medical costs, and even endanger life. Therefore, reduction of complications and optimizing perioperative management are key issues that urgently need to be addressed in clinical practice.

Eligibility

Primary outcome measure(s)

• Complication — hospital discharge, an average of 10 days
  This includes embolic events, pulmonary complication, wound complication, acute kidney injury, death. Diagnose according to radiologic examination, sign and symptom

Trial sites (1)

More Second Affiliated Hospital, Zhejiang University, School of Medicine trials in China