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Clinical Trials in China / NCT07627516
Recruiting Not applicable

Clinical Study of the Efficacy and Safety of Spinal Cord Stimulation in Patients With Limb Motor Dysfunction Following Stroke

NCT07627516 · tracked via the Priya Life Science China tracker
Sponsor
Second Affiliated Hospital, Zhejiang University, School of Medicine
Phase
Not applicable
Started
2026-01-01
Last updated
2026-06-04

Condition(s) studied

Stroke

Investigational drug(s) / intervention(s)

Spinal cord stimulator

Spinal cord stimulator: This trial is a single-arm, self-controlled exploratory clinical study. Participants will undergo surgical implantation of spinal cord stimulation electrodes and receive programming and optimization of spinal cord stimulation parameters.

Study summary

To assess the efficacy and safety of spinal cord stimulation in treating post-stroke limb motor disorders, we propose to conduct a clinical trial. This study seeks to accumulate additional clinical experience with spinal cord stimulation in patients suffering from post-stroke limb motor disorders and to enhance their quality of life.

Eligibility

Sex
ALL
Min age
20 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: 1. Hemiparesis resulting from a single ischemic or hemorrhagic stroke, with a disease duration of ≥6 months. 2. Aged between 20 and 80 years (inclusive). 3. Received regular rehabilitation therapy after stroke but with poor recovery of limb motor function; Fugl-Meyer Assessment upper extremity score \>7 and \<45, and lower extremity score \>5 and \<30. 4. Partially preserved sensory function. Exclusion Criteria: 1. Severe systemic diseases (e.g., neurological disorders other than stroke, cancer, severe circulatory or respiratory diseases, liver or kidney failure, etc.) or other conditions that may impair the subject's motor or cognitive function. 2. Presence of spinal cord-related nerve compression that could cause severe functional impairment. 3. Women who are pregnant or breastfeeding. 4. Use of anticoagulant, antiplatelet, antispasmodic, or antiepileptic medications prior to enrollment or during the study period. 5. Severe joint contracture that, in the clinical investigator's opinion, precludes participation in the study. 6. Severe mental illness or intellectual disability that prevents cooperation with treatment or follow-up questionnaires, with a Mini-Mental State Examination (MMSE) score \<24. 7. Presence of other implanted medical devices. 8. Severe claustrophobia.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
The Second Affiliated Hospital, Zhejiang University School of Medicine Hangzhou Zhejiang Recruiting

More Second Affiliated Hospital, Zhejiang University, School of Medicine trials in China

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07627516 on ClinicalTrials.gov ↗ ← All trials in China