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Clinical Trials in China / NCT07529626
Recruiting Observational

Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer

NCT07529626 · tracked via the Priya Life Science China tracker
Sponsor
Shanghai Zhongshan Hospital
Phase
Observational
Started
2026-05-11
Last updated
2026-06-29

Condition(s) studied

Pancreatic Tumor, BenignPancreatic Cancer, AdultPancreatic Cancer Resectable

Study summary

This is a prospective, observational cohort study (MIND-PANC) to explore the associations of chronic psychological stress with disease progression, treatment outcomes, and prognosis of pancreatic cancer.

Researchers will ask participants to fill out simple questionnaires about their mood, worries, and sleep at the start of the study and at regular follow-up visits. The study will also collect a small blood sample (leftover from routine care) to measure stress-related markers.

Investigators hypothesize that pancreatic cancer patients who have higher levels of ongoing psychological stress (such as anxiety, depression, or poor sleep) tend to have shorter survival times, a higher chance of recurrence, and a poorer response to treatment, compared to patients with lower stress levels.

Eligibility

Sex
ALL
Min age
18 Years
Max age
Healthy volunteers
No
Inclusion Criteria: * Age ≥ 18 years. * Histologically or cytologically confirmed diagnosis of pancreatic cancer, or other pancreatic diseases. * Conscious, with basic reading/writing or communication skills, able to understand and complete the questionnaire assessments (either independently, with assistance from research staff, or with help from a family member). * Voluntarily agree to participate in this study and sign a written informed consent form. Exclusion Criteria: * Presence of severe cognitive impairment (e.g., dementia, disturbance of consciousness) or a definite history of psychiatric disorders, judged by the investigator as unable to comply with the study assessments, and without a family member who can help complete the questionnaire assessments. * Presence of other severe, uncontrolled systemic diseases (e.g., severe heart, lung, or kidney failure), with an estimated life expectancy \< 3 months as judged by the investigator. * Inability to understand Chinese or presence of severe visual/hearing impairment that affects completion of the questionnaire assessments, and without a family member who can help complete the questionnaire assessments.

Primary outcome measure(s)

Trial sites (3)

FacilityCityRegionStatus
the Third Xiangya Hospital of Central South University Changsha Hunan Not Yet Recruiting
Zhongshan Hospital Affiliated to Fudan University Shanghai Shanghai Municipality Recruiting
The First Affiliated Hospital of Xi'an Jiao Tong University Xi’an Shanxi Not Yet Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07529626 on ClinicalTrials.gov ↗ ← All trials in China