LY4395089: Administered orally
Mirikizumab - Intravenous (IV): Administered IV
Mirikizumab - Subcutaneous (SC): Administered SC
The main purpose of this study is to see how the safety and efficacy of a farnesoid X receptor (FXR) agonist (LY4395089), given together with mirikizumab compares with mirikizumab (alone) in adults with moderately to severely active Crohn's disease (CD). This study is part of the IIBD master protocol and will last approximately 62 weeks.
| Facility | City | Region | Status |
|---|---|---|---|
| Mayo Clinic in Arizona - Scottsdale | Scottsdale | Arizona | Suspended |
| Biopharma Informatic, LLC | Los Angeles | California | Not Yet Recruiting |
| Om Research LLC | Oxnard | California | Recruiting |
| South Denver Gastroenterology | Englewood | Colorado | Recruiting |
| Gastro Health Research - Miami | Miami | Florida | Recruiting |
| Ezy Medical Research | Miami Lakes | Florida | Recruiting |
| Atlanta Gastroenterology Associates - Peachtree Dunwoody | Atlanta | Georgia | Recruiting |
| Rush University Medical Center | Chicago | Illinois | Not Yet Recruiting |
| Cotton O'Neil Digestive Health Center | Topeka | Kansas | Recruiting |
| Gastroenterology Associates of Western Michigan, PLC d.b.a. West Michigan Clinical Research Center | Wyoming | Michigan | Not Yet Recruiting |
| KAD Clinical Research | St Louis | Missouri | Recruiting |
| Vector Clinical Trials | Las Vegas | Nevada | Recruiting |
| One of a Kind Clinical Research Center - Kingwood | Kingwood | Texas | Not Yet Recruiting |
| Southern Star Research Institute | San Antonio | Texas | Recruiting |
| AZ Maria Middelares | Ghent | Belgium | Not Yet Recruiting |
| UZ Gent | Ghent | Belgium | Not Yet Recruiting |
| UZ Leuven | Leuven | Belgium | Not Yet Recruiting |
| AZ Delta vzw | Roeselare | Belgium | Not Yet Recruiting |
| Loema Instituto de Pesquisa Clinica | Campinas | Brazil | Not Yet Recruiting |
| Fundação Universidade de Caxias do Sul (FUCS) | Caxias do Sul | Brazil | Not Yet Recruiting |
| Centro Digestivo de Curitiba | Curitiba | Brazil | Not Yet Recruiting |
| Centro de Pesquisa Clínica de Marília - CPCLIM | Marília | Brazil | Not Yet Recruiting |
| CPHosp Medicina, Ensino e Pesquisa (CPQuali) | São Paulo | Brazil | Not Yet Recruiting |
| CPCLIN | São Paulo | Brazil | Not Yet Recruiting |
| BR Trials - Ensaios Clinicos e Consultoria | São Paulo | Brazil | Not Yet Recruiting |
| Clínica Hepatogastro JK | São Paulo | Brazil | Not Yet Recruiting |
| CEDOES | Vitória | Brazil | Not Yet Recruiting |
| Prairie Institute of Liver and Luminal Advanced Research Ltd (PILLAR) | Lethbridge | Canada | Not Yet Recruiting |
| London Digestive Disease Institute | London | Canada | Suspended |
| Tdda Inc. | Vaughan | Canada | Recruiting |
| The Second Xiangya Hospital of Central South University | Changsha | China | Recruiting |
| Changzhou Second People's Hospital | Changzhou | China | Recruiting |
| The First Affiliated Hospital, Sun Yat-sen University | Guangzhou | China | Recruiting |
| The Second Affiliated hospital of Zhejiang University school of medicine | Hangzhou | China | Recruiting |
| Huizhou Central People's Hospital | Huizhou | China | Recruiting |
| The Second Affiliated Hospital of Soochow University | Suzhou | China | Recruiting |
| The Second Affiliated Hospital YuYing Childens Hospital of Wenzhou Medical university | Wenzhou | China | Recruiting |
| Zhongshan Hospital Affiliated to Xiamen University | Xiamen | China | Recruiting |
| Affiliated Hospital of Jiangsu University | Zhenjiang | China | Recruiting |
| Charité Universitaetsmedizin Berlin - Campus Mitte | Berlin | Germany | Not Yet Recruiting |
+ 30 more sites — see the full list on the official registry below.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07483099 on ClinicalTrials.gov ↗ ← All trials in China