🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Writer Login
Latest
Clinical Trials in China / NCT07390383
Recruiting Phase 2

A Phase II Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumour[Substudy 04]

NCT07390383 · tracked via the Priya Life Science China tracker
Sponsor
Nanjing Leads Biolabs Co.,Ltd
Phase
Phase 2
Started
2026-04-13
Last updated
2026-05-13

Condition(s) studied

Advanced Solid Tumour

Investigational drug(s) / intervention(s)

LBL-024 for InjectionCapecitabine tabletsTislelizumab InjectionOxaliplatin injection

LBL-024 for Injection: Intravenous infusion

Capecitabine tablets: Oral administration

Tislelizumab Injection: Intravenous infusion

Oxaliplatin injection: Intravenous infusion

Study summary

An Open-label, Multicenter, Phase II Clinical Study to Evaluate the Efficacy and Safety of LBL-024 in Combination With Other Drugs for the Treatment of Patients With Advanced Solid Tumour.

Eligibility

Sex
ALL
Min age
18 Years
Max age
Healthy volunteers
No
Inclusion Criteria: 1. Agree to follow the trial treatment regimen, visit schedule, laboratory test, and other requirements of the protocol, and voluntarily enroll in the study and sign the written informed consent. 2. Age ≥ 18 years at the time of signing the informed consent. 3. Eastern Cooperative Oncology Group (ECOG) performance status score of 0-1. 4. The expected survival time is at least 12 weeks. 5. According to the evaluation of RECIST 1.1 standard, the subjects enrolled have at least one measurable lesion. 6. Patients with histologically confirmed unresectable locally advanced or metastatic gastric/gastroesophageal junction (G/GEJ) adenocarcinoma. 7. There is adequate organ and bone marrow function,Conforms to laboratory test results. 8. Males with fertility and females of childbearing age are willing to take effective contraceptive measures From the signing of the informed consent form to within 6 months after the last administration of the trial drug (including abstinence, intrauterine device, various hormonal contraception, correct use of contraception Sets,etc); Women of childbearing age include pre-menopausal women and women within 2 years after menopause. Women of childbearing age must have a negative pregnancy test within 7 days before the first trial drug is administered. Exclusion Criteria: 1. Participation in clinical studies of antineoplastic agents within 4 weeks before the first use of study drug,or is expected to receive any other form of systemic anti-tumor therapy outside the protocol during the study. 2. Use of immunomodulatory drugs within 2 weeks before the first use of study drug,Including but not limited to thymopeptide, interleukins, interferon, etc. 3. Patients with active, or who have had and have the possibility of recurrence of autoimmune diseases. 4. Patients with clinically uncontrollable pleural effusion, pericardial effusion, ascites, and those requiring repeated drainage or medical intervention. 5. The patient has a Medical history of immunodeficiency, including HIV antibody positive. 6. Active hepatitis B or active hepatitis C. 7. Women during pregnancy or lactation. 8. The investigator believes that the subject has other conditions that may affect compliance or are not suitable for participating in this study.

Primary outcome measure(s)

Trial sites (7)

FacilityCityRegionStatus
Beijing GoBroad Hospital Beijing Beijing Municipality Not Yet Recruiting
Beijing Cancer Hospital Beijing Beijing Municipality Recruiting
The Fourth Hospital of Hebei Medical University Shijiazhuang Hebei Not Yet Recruiting
Shandong Cancer Hospital Jinan Shandong Not Yet Recruiting
The Affiliated Hospital of Qingdao University Qingdao Shandong Not Yet Recruiting
Shanxi Provincial Cancer Hospital Taiyuan Shanxi Not Yet Recruiting
Tianjin Medical University Cancer Institute & Hospital Tianjin Tianjin Municipality Not Yet Recruiting

More Nanjing Leads Biolabs Co.,Ltd trials in China

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07390383 on ClinicalTrials.gov ↗ ← All trials in China