Longitudinal Follow-up and Health-Related Outcomes in Liver Transplant Recipients and Living Donors

NCT07301853 · tracked via the Priya Life Science China tracker

Sponsor

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase

Observational

Started

2025-11-24

Last updated

2025-12-24

Condition(s) studied

Living Donor Liver Transplantation RecipientsDeceased Donor Liver Transplantation RecipientsLiving Liver Donor

Investigational drug(s) / intervention(s)

liver transplantationLiving Donor Hepatectomy

liver transplantation: Patients undergo standard liver transplantation according to clinical protocols. Postoperative management and follow-up are conducted per routine standard of care. Clinical data, including survival, adverse events, and quality of life (assessed by questionnaires/scales), are collected observationally at regular follow-up intervals.

Living Donor Hepatectomy: Living donors undergo standard hepatectomy procedures. Postoperative recovery and long-term health outcomes are monitored through routine follow-up visits and assessments.

Study summary

This prospective cohort study aims to identify risk factors for postoperative adverse events in liver transplant recipients and living donors. By collecting comprehensive clinical data and conducting systematic long-term follow-up, the researchers intend to establish a specialized, standardized, and individualized follow-up management system. The ultimate goal is to optimize intervention strategies and improve patient prognosis and quality of life for both recipients and donors.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: 1. Patients undergoing liver transplantation or living donor hepatectomy at the study center (living donor should be approved by the hospital ethics committee for living organ donation); 2. Age 18 years or older; 3. Willing to participate in the long-term follow-up management program; 4. Signed informed consent form; Exclusion Criteria: 1. Patients undergoing combined organ transplantation 2. Patients with severe mental illness or cognitive impairment who are unable to cooperate with follow-up assessments. 3. Donors whose surgery is aborted intraoperatively for any reason. 4. Unable or unwilling to comply with the long-term follow-up schedule.

Primary outcome measure(s)

Long-term Incidence of Postoperative Adverse Events — From date of surgery up to 20 years
Evaluation of the cumulative incidence of postoperative complications

Trial sites (1)

Facility	City	Region	Status
The Second Affiliated Hospital Zhejiang University School of Medicine	Hangzhou	Zhejiang	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07301853 on ClinicalTrials.gov ↗ ← All trials in China