A Phase II Study To Evaluate the Efficacy And Safety Of HRS-1301 In Participants With Dyslipidemia

Inclusion Criteria: 1. Male and female ≥ 18 years old, who is able and willing to provide a written informed consent 2. BMI ≥ 18.0 kg/m2 3. Clinically diagnosed with ASCVD and LDL-C ≥ 1.8 mmol/L OR, if no history of ASCVD, has intermediate to high risk of developing ASCVD and LDL-C ≥ 2.6 mmol/L 4. Male and female subjects of childbearing potential and their partners must have no plans to donate sperm or become pregnant during the entire study period and for 2 weeks after the last dose, and agree to use contraceptive methods as specified in the protocol Exclusion Criteria: 1. TG \> 5.6 mmol/L 2. Diagnosed with homozygous familial hypercholesterolemia (HoFH) 3. Acute ischemic ASCVD events within 12 months before screening, or during the screening and run-in phase 4. Heart failure with New York Heart Association (NYHA) Class III-IV 5. Malignant tumors within 5 years 6. Received or is regularly receiving LDL or plasma apheresis within 12 months before screening 7. History or presence of severe gastrointestinal, hepatic, or renal diseases, or other known diseases that may interfere with drug absorption, distribution, metabolism, or excretion 8. Uncontrolled diabetes mellitus and/or hypertension 9. Has undergone transplantation of any vital organ, such as lung, liver, heart, bone marrow, or kidney