temporal interference: In this intervertion, patients with SEEG operation will take temporal interference (TI) stimulation and the deep brain EEG will be monitorated through the entire experiment.
Study summary
This study evaluates the effect of temporal interference (TI) stimulation on biomarkers in patients with temporal lobe epilepsy (TLE) under stereo-electroencephalography (SEEG), and provides theoretical basis for non-invasive TI treatment of temporal lobe epilepsy.
Eligibility
Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria:
* Clinical diagnosis of drug refractory epilepsy and temporal lobe epilepsy;
* Patients undergoing SEEG;
* Able to cooperate the treatment and related inspection;
* Fully understands and signs informed consent.
Exclusion Criteria:
* Patients with temporal plus epilepsy;
* In status epilepticus;
* With other severe disease;
* Pregnancy or lactation women;
* Unable to tolerate SEEG or TI;
* At the same time to participate in other clinical trials;
* Withdraw consent procedure.
Primary outcome measure(s)
Number of interictal electrophysiological biomaker changes in epilepsy — 24 hours after TI stimulation Electrophysiological biomarkers changes recorded by SEEG through the experiment.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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