The Effect of Serum Calcium Levels on Postoperative Pain: A Prospective Observational Study

NCT06957158 · tracked via the Priya Life Science China tracker

Sponsor

The Second Affiliated Hospital of Chongqing Medical University

Phase

Observational

Started

2025-07

Last updated

2025-06-27

Condition(s) studied

Postoperative Pain

Investigational drug(s) / intervention(s)

Peripheral venous bloodArterial blood

Peripheral venous blood: Peripheral venous blood was collected before and after the surgery to measure the total serum calcium levels.

Arterial blood: Arterial blood was collected before anesthesia induction and after removal of the artificial airway to measure ionized calcium levels.

Study summary

This is a prospective observational study. To investigate the effect of serum calcium levels on postoperative pain in patients undergoing abdominal surgery, and to determine whether changes in serum calcium levels are a risk factor for postoperative pain.

Eligibility

Sex

ALL

Min age

18 Years

Max age

70 Years

Healthy volunteers

Inclusion Criteria: * Aged 18-70 years old * American Society of Anesthesiologists Classification I-III * Patients undergoing elective abdominal surgery under general anesthesia * Patients participate voluntarily and sign an informed consent form Exclusion Criteria: * Patients with a history of severe disease * Patients with chronic preoperative pain and/or long-term analgesic use * Patients with hearing disorders or verbal communication difficulties * Patients with psychiatric disorders or cognitive dysfunction * Patients requiring mechanical ventilation or ICU admission after surgery * Patients with a history of substance or alcohol abuse Patients who could not cooperate with the study for any reason

Primary outcome measure(s)

The incidence of pain NRS score ≥6 within 48 hours after surgery — From the end of the surgery to 48 hours after surgery
NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）

Trial sites (1)

Facility	City	Region	Status
The Second Affiliated Hospital of Chongqing Medical University	Chongqing	Chongqing Municipality	Recruiting

More The Second Affiliated Hospital of Chongqing Medical University trials in China

Effect of Ciprofol Injection on Postoperative Cognitive Function Active, not recruiting

Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for NARDS Recruiting

A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B) Recruiting

Development and Validation of a Risk Prediction Model for Postoperative Visceral Pain in Abdominal Surgery Patients Starting soon

The Effect of General Anesthesia with Remimazolam and Propofol on Rhythmic State and Cognitive Function Starting soon

Other trials for the same condition

Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip Surgery Starting soon

Sacral Canal Block for Hip Replacement the Efficacy and Safety of Controlled Intraoperative Hypotension Recruiting

Electroencephalogram Changes Induced by Transcutaneous Electrical Acupoint Stimulation Recruiting

Analysis of the Incidence and Risk Factors of Chronic Pain After Cesarean Section Recruiting

Effect of Liposomal Bupivacaine TAPB Combined With Oxycodone PCIA on Postoperative Gastrointestinal Recovery in Patients Undergoing Major Abdominal Surgery Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06957158 on ClinicalTrials.gov ↗ ← All trials in China