Different Injection Speed on Local Anaesthetic Spread of ESPB

NCT06936904 · tracked via the Priya Life Science China tracker

Sponsor

Nanjing First Hospital, Nanjing Medical University

Phase

Not applicable

Started

2025-04-21

Last updated

2025-05-22

Condition(s) studied

Erector Spinae Plane Block

Investigational drug(s) / intervention(s)

injection speed

injection speed: Patients undergoing CT-guided lung nodule localization were selected for the study, and ultrasound-guided erector spinae plane block was performed before surgery with different injection speed.

Study summary

The aim of this clinical trial is to investigate the effect of different injection speeds on the spread of local anesthetic during ultrasound-guided erector spinae plane block (ESPB) in patients undergoing CT-guided lung nodule localization. The primary question addressed is whether a high injection speed (30 ml delivered within 30 seconds) produces a different local anesthetic distribution compared with a lower injection speed (30 ml delivered within 180 seconds).

Eligibility

Sex

ALL

Min age

18 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: Patients scheduled for CT-guided lung nodule localization under local anesthesia will be selected 1. aged 18-80 years 2. BMI 18-30 kg/m² 3. ASA classification I-III Exclusion Criteria: 1. Allergy to the study drug or to local anesthetics 2. History of opioid abuse 3. Previous infection at the ESPB or PVB puncture site 4. Peripheral neuropathy 5. Dysfunction of blood coagulation

Primary outcome measure(s)

Spread of local anesthetic into the paravertebral space — 30 minutes after completion of the ESPB block
Observation of local anesthetic spread into the paravertebral space with CT by a researcher who was blinded to group allocation

Trial sites (1)

Facility	City	Region	Status
Nanjing First Hospital	Nanjing	Jiangsu	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06936904 on ClinicalTrials.gov ↗ ← All trials in China