This clinical trial study aims to detect the imaging characteristics of patients with hepatic encephalopathy (HE) using 7-Tesla (7T) magnetic resonance imaging (MRI).
Eligibility
Sex
ALL
Min age
18 Years
Max age
89 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Patients with clinical suspected or diagnosed hepatic encephalopathy according to relevant guidelines.The patient's education level is above primary school level.
* Regular follow-up.
Exclusion Criteria:
* Contraindications to MRI.
* Patients with cerebrovascular disease, brain tumors, epilepsy, other neurodegenerative disease.
Primary outcome measure(s)
Functional connectivity and structural alterations between individuals with different subtypes of HE and healthy subjects. — 5 years Functional connectivity calculation is mainly based on the BOLD sequence, which is used to describe the degree of connectivity between different brain regions and reflect the functional activity of the brain. Gray matter (GM) morphological destruction, cortical thickness, and subcortical nuclear volume in patients with hepatic encephalopathy were analyzed based on structural magnetic resonance imaging（sMRI）.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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