Establishment of a Predictive Model for Post-dural Puncture Headache

Condition(s) studied

Investigational drug(s) / intervention(s)

Supplement fluids: To ensure optimal recovery and manage potential complications, patients are advised to supplement fluids by increasing their oral intake or receiving intravenous fluids as necessary. Bed rest is recommended to reduce physical strain and promote healing. Additionally, a blood patch procedure may be performed to alleviate symptoms such as headaches that can occur after certain medical procedures, particularly spinal taps. This involves injecting a small amount of the patient's own blood into the epidural space to seal any leaks of cerebrospinal fluid, thereby providing relief and aiding in recovery. Proper monitoring and follow-up care are essential to ensure the effectiveness of these interventions

Study summary

The goal of this clinical trial is to establish a predictive model for post-dural puncture headache. The main questions it aims to answer are:

Changes in intracranial pressure after spinal puncture (or lumbar puncture). When post-dural puncture headache occurs, the optic nerve sheath diameter (ONSD) change When the optic nerve sheath diameter (ONSD) and (or) Intraocular Pressure (IOP) reaches a certain threshold, does proactive treatment reduce the incidence of postoperative headaches? Researchers will measure the optic nerve sheath diameter (ONSD) using ultrasound and ( or ) magnetic resonance imaging (MRI) before and after spinal puncture.

Researchers will measure the Intraocular Pressure (IOP) using ICARE before and after spinal puncture.

Participants will:

Undergo ultrasound and (or) magnetic resonance imaging (MRI) examinations before and after spinal puncture Undergo ICARE examinations before and after spinal puncture

Eligibility

Primary outcome measure(s)

• Optic nerve sheath diameter (ONSD) measurement by MRI — 1 hour before dural puncture
  ONSD Measurement by MRI
• Optic nerve sheath diameter (ONSD) measurement by MRI — 24 hours after dural puncture
  ONSD Measurement by MRI
• Optic nerve sheath diameter (ONSD) measurement by B ultrasound — 1 hour before dural puncture
  ONSD Measurement by B ultrasound
• Optic nerve sheath diameter (ONSD) measurement by B ultrasound — 8 hours after dural puncture
  ONSD Measurement by B ultrasound
• Optic nerve sheath diameter (ONSD) measurement by B ultrasound — 24 hours after dural puncture
  ONSD Measurement by B ultrasound
• Optic nerve sheath diameter (ONSD) measurement by B ultrasound — 48 hours after dural Puncture
  ONSD Measurement by B ultrasound
• Intraocular Pressure messurement — 1 Hour before dural Puncture
  Intraocular Pressure measurement by Icare
• Intraocular Pressure messurement — 8 hours after dural puncture
  Intraocular Pressure measurement by Icare
• Intraocular Pressure messurement — 24 hours after dural puncture
  Intraocular Pressure measurement by Icare
• Intraocular Pressure messurement — 48 hours after dural puncture
  Intraocular Pressure measurement by Icare

Trial sites (1)

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