Exploring the Minimum Effective Concentration and Volume of Ropivacaine for Sacral Plexus Anesthesia

Condition(s) studied

Investigational drug(s) / intervention(s)

Low-dose ropivacaine: 0.5 ml/Kg ropivacaine

Medium-dose of ropivacaine: 1ml/Kg ropivacaine

High-dose ropivacaine: 1.5 ml/Kg ropivacaine

Study summary

The goal of this clinical trial is to explore the minimum effective concentration and volume of ropivacaine for sacral plexus anesthesia. The main questions it aims to answer are:

* The distribution of different volumes of ropivacaine after caudal anesthesia
* The blockade level after caudal anesthesia with varying doses
* The minimum effective concentration of ropivacaine among pediatric patients of different age groups Researchers will inject different doses or concentrations of ropivacaine into the caudal canal to observe the drug's spread range, the level of blockade, and the duration of its effect.

Participants will:

* Undergo magnetic resonance imaging (MRI) examinations before and after caudal anesthesia
* Will be detected the blockade level after caudal anesthesia

Eligibility

Primary outcome measure(s)

• Distribution and block plane in the spinal canal after caudal injection of different doses of ropivacaine. — 30 minutes
  MRI scan will be performed before and after 0.5 ml/Kg, 1,ml/Kg, or 1.5ml/Kg ropivacaine injection,
• The blockade level after caudal anesthesia with varying doses — 60 minutes
  The blockade level will be tested 15 min and 30min after 0.5 ml/Kg, 1,ml/Kg, or 1.5ml/Kg ropivacaine injection. The infrared imaging technology will be employed to test the blockade level.
• The minimum effective concentration of ropivacaine among pediatric patients of different age groups — 2 days
  The fixed capacity requires the minimum effective concentration by changing the concentration

Trial sites (1)

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