Sedative Effect During Drug-induced Sleep EndoscopyObstructive Sleep Apnea (OSA)
Investigational drug(s) / intervention(s)
Remimazolam and PropofolPropofolMidazolam and propofol
Remimazolam and Propofol: Application of Remimazolam and Propofol to induce sleep
Propofol: Application of Propofol to induce sleep
Midazolam and propofol: Application of Midazolam and Propofol to induce sleep
Study summary
This study helps patients find the optimal sedation regimen in drug-induced sleep endoscopy
Eligibility
Sex
ALL
Min age
18 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria:
* Patients diagnosed with sleep apnea hypopnea syndrome were included
Exclusion Criteria:
* Patients were excluded if they had nasal obstruction, significantly deviated nasal septum, nasal turbinate hypertrophy, or nasal polyps. Patients with uncontrolled heart failure, renal insufficiency, diabetes, or hyperthyroidism were also excluded. Patients were also excluded if taking medications that could affect upper airway muscle function, such as ben- zodiazepines and muscle relaxants.
Primary outcome measure(s)
sedation success rate — During procedure (From the start of drug induced sleep endoscopy to the complete awakening of the patient) a composite measure including completion of the DISE, no requirement for rescue sedative medication, and no requirement for more than 5 top-up doses of the trial medication after the initial dose.
Trial sites (1)
Facility
City
Region
Status
Respiratory Endoscopy Center of Tianjin Medical University General Hospital
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time on our Cookie Policy page. See also our Privacy Policy.