Effects of Vitamin D Supplementation on Postoperative Rehabilitation in Hip and Knee Osteoarthritis Patients

Condition(s) studied

Investigational drug(s) / intervention(s)

Vitamin D: Vitamin D oral supplementation

Study summary

The goal of this clinical trial is to learn if vitamin D supplementation affects postoperative rehabilitation in osteoarthritis patients who underwent joint arthroplasty. The main questions it aims to answer are:

Does oral vitamin D supplementation for a period of time after joint arthroplasty affect the postoperative recovery speed in patients who have vitamin D deficiency? Does oral vitamin D supplementation after joint arthroplasty affect the long-term recovery of joint functions in patients who have vitamin D deficiency?

Participants will:

Take vitamin D oral supplement every day for 3 months. Visit the clinic in 1, 3, 6, 12 months after joint replacement surgery for checkups and tests.

Eligibility

Primary outcome measure(s)

• Knee joint function — From enrollment to the end of treatment at 1 year
  Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Pain ranging from 0 to 20 points; stiffness, 0 to 8 points; and physical function, 0 to 68 points. Higher scores represent worse pain, stiffness, and functional limitations.
• Hip joint function — From enrollment to the end of treatment at 1 year
  Harris Hip Score. The maximum score possible is 100. Results can be interpreted with the following: \<70 = poor result; 70-80 = fair, 80-90 = good, and 90-100 = excellent.
• Muscle strength — From enrollment to the end of treatment at 1 year
  Using portable muscle strength tester to measure flexor and extensor muscle strength of knee or hip joint

Trial sites (1)

More Second Affiliated Hospital, Zhejiang University, School of Medicine trials in China