Multidisciplinary Preoperative Risk Evaluation and the Corresponded Pre ERAS intervention
Multidisciplinary Preoperative Risk Evaluation and the Corresponded Pre ERAS intervention: The operative risk factors are multidisciplinary evaluated and the corresponded multimodal measures are used to optimize the whole condition of the elderly patient undergo spinal fusion surgery for his/her safty, early and fully recovery.
Study summary
This study aims to evaluate the value of preoperative risk factor evaulation combined with perioperative ERAS measures in improving the clinical prognosis of elderly patients undergo the spinal fusion.
Eligibility
Sex
ALL
Min age
75 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* 1.Age ≥75 years old;
* 2.Have degenerative spinal diseases, including cervical, thoracic and lumbar spine diseases;
* 3.With severe neurological symptoms fail to conservative treatment and have to undergo the spinal fusion surgery;
* 4.No serious cognitive impairment (MoCA score ≥8);
* 5.No surgical contraindications;
* 6.Anesthesia assessment patients can safely undergo surgery;
* 7.Patients who voluntarily participate in and sign informed consent, can independently complete effective questionnaires, and are willing to follow up according to clinical requirements.
Exclusion Criteria:
* 1.Patients who could not cooperate with doctors to complete preoperative evaluation and postoperative follow-up;
* 2.Patients requiring spinal intervention due to spinal infection, fracture or metastatic disease;
* 3.Patients with cerebrovascular accidents in the last 30 days;
* 4.Patients with hepatic encephalopathy or acute active hepatitis;
* 5.Patients with severe renal insufficiency with creatinine\>2.5mg/dL or undergoing hemodialysis;
* 6.Patients with severe lung and cardiovascular diseases, coagulation disorders, and anesthesia contraindications;
* 7.Patients with poorly controlled diabetes (HBAlc\>8.0%);
* 8.Patients who are participating in clinical trials of other drugs or medical devices;
* 9.Patients requiring emergency surgery;
* 10.Patients who are considered by the investigator to be unable to participate in this clinical trial due to other circumstances.
Primary outcome measure(s)
Comprehensive Complication Index — 24 weeks postoperation The Comprehensive Complication Index (CCI) is based on the complication grading by the Clavien-Dindo Classification and captures every complication that occurred after an intervention. The overall morbidity is reflected on a scale from 0 (no complication) to 100 (death) and reflects the gravity of this overall complication burden on the patients. CCI can be calculated using online CCI calculator (https://cci-calculator.com/cciCalculator), which is a tool to support the assessment of patients' overall morbidity after an intervention.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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