Multicenter Cohort Study of ESD and Chemo-radiotherapy for High-risk Early-stage Esophageal Cancer

NCT06385717 · tracked via the Priya Life Science China tracker

Sponsor

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase

Observational

Started

2024-05-01

Last updated

2024-04-26

Condition(s) studied

Esophagus Cancer

Investigational drug(s) / intervention(s)

chemo-radiation

chemo-radiation: different Chemo-radiotherapy regimen

Study summary

This multicenter, prospective observational cohort study has the potential to optimize individualized chemoradiotherapy regimen for early-stage esophageal cancer patients who have received endoscopic submucosal dissection.

Eligibility

Sex

ALL

Min age

18 Years

Max age

75 Years

Healthy volunteers

Inclusion Criteria: * 1\. Esophageal cancer patients who are pathologically confirmed as pT1a-MM stage or pT1b stage after endoscopic submucosal dissection； 2. No definite contraindications for chemo-radiotherapy； 3. Informed consent has been signed； 4. Refused surgery after endoscopic submucosal dissection. Exclusion Criteria: * 1\. Severe heart, brain, lung disease or renal dysfunction; 2. Previous history of other malignancies; 3. Prior radiation or chemotherapy 4. Researchers consider it inappropriate to participate in this experiment

Primary outcome measure(s)

Incidence of toxic events — 2026.2
esophageal stenosis, radiation pneumonitis, etc

Trial sites (2)

Facility	City	Region	Status
The Second Affiliated Hospital of Zhejiang University School of Medicine	Hangzhou	Zhejiang	Recruiting
The Second Affiliated Hospital of Zhejiang University, School of Medicine	Hangzhou	China	Not Yet Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06385717 on ClinicalTrials.gov ↗ ← All trials in China