Early Body Temperature Targets and Relationship With Prognosis in Patients With Heat Stroke

NCT05921682 · tracked via the Priya Life Science China tracker

Sponsor

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase

Observational

Started

2023-05-28

Last updated

2024-09-20

Condition(s) studied

Heat Stroke

Investigational drug(s) / intervention(s)

observation

observation: This study is an observational study. Patients will receive conventional cooling measures and organ function support.

Study summary

The goal of this observational study is to explore the optimal target body temperature in first 24 hours and the relationship between body temperature and adverse outcomes of heat stroke.

The main questions it aims to answer are:

* the optimal target body temperature at 0.5 h, 2 h, and the lowest body temperature of heat stroke.
* the best body temperature at the cutting point of stop cooling.
* The relationship between the volume and speed of ice saline infusion and the cooling effect.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * ≥ 18 years; ② diagnosed as heat stroke; ③ Informed consent from patients or family members. Exclusion Criteria: * need immediate cardiopulmonary resuscitation; ② transferred from another hospital; ③ with severe underlying organ insufficiency; ④ pregnant women.

Primary outcome measure(s)

mortality — up to 90 days
Number of participants who dead during hospitalization
organ damage — up to 90 days
Number of participants with organ damage, including but not limited to brain, lung, heart, kidney, liver and coagulation

Trial sites (6)

Facility	City	Region	Status
Yiwu Central Hospital	Yiwu	Zhejiang	Recruiting
Dongyang People's Hospital	Dongyang	China	Recruiting
The Second Affiliated Hospital of Zhejiang University School of Medicine	Hangzhou	China	Recruiting
Jinhua Municipal Central Hospital	Jinhua	China	Recruiting
Jinhua People's Hospital	Jinhua	China	Recruiting
Lanxi People's Hospital	Lanxi	China	Recruiting

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Other trials for the same condition

Non-inferiority Study of the Effect of Non-cooling Blanket on Body Temperature in Patients With Heat Stroke Recruiting

Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients Recruiting

Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Heat Stroke Starting soon

Mechanism Study of G Protein-coupled Receptor 81 in Multiple Organ Dysfunction of Heat Stroke Active, not recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05921682 on ClinicalTrials.gov ↗ ← All trials in China