CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection

NCT05433467 · tracked via the Priya Life Science China tracker

Sponsor

Northern Jiangsu People's Hospital

Phase

Not applicable

Started

2022-05-01

Last updated

2025-08-13

Condition(s) studied

Cirrhosis, LiverHepatocellular Carcinoma

Investigational drug(s) / intervention(s)

CT-guided localization for micro hepatocellular carcinoma before surgical resection

CT-guided localization for micro hepatocellular carcinoma before surgical resection: After preoperative preparation was completed, on the day of surgery, disposable pulmonary nodular localization needle (Ningbo Sonjiecang Biological Technology Co., LTD., Model: SS510-10) was used for the localization of micro hepatocellular carcinoma that could be found by preoperative CT enhancement or MRI. After the micro hepatocellular carcinoma was located under the guidance of CT, and then the patient was sent to the operating room. During the operation, the lesion was removed according to the tail line of the positioning needle and the position of the positioning needle.

Study summary

In this project, the preoperative anatomical location of micro hepatocellular carcinoma under the guidance of CT can provide guidance for accurate surgical resection. It may also shorten the operation time and reduce intraoperative bleeding.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: 1. Be at least 18 years old and give informed consent to participate in the study 2. A preoperative (clinical, radiological, or histological) diagnosis of cirrhosis of the liver due to any cause. 3. micro hepatocellular carcinoma (diameter less than 1cm). 4. Preoperative CT plain scan could not find the lesion, and preoperative B-ultrasound could not find the lesion. 5. Preoperative CT enhancement or MRI can detect the lesion. Exclusion Criteria: 1. Child-Pugh grade C 2. Uncontrolled Hypertension 3. Severe lung dysfunction 4. Severe cardiac dysfunction

Primary outcome measure(s)

The position of the needle — During operation
The distance (mm) of the needle to the edge of hepatocellular carcinoma

Trial sites (1)

Facility	City	Region	Status
Clinical Medical College, Yangzhou University	Yangzhou	Jiangsu	Recruiting

More Northern Jiangsu People's Hospital trials in China

THRIVE Improves Early Postoperative Atelectasis in Long-Time Non-Tracheal Intubation Anesthesia for Gastrointestinal Endoscopy: a Clinical Study Active, not recruiting

The Effect of Laparoscopic Splenectomy on Liver Reserve Function for Cirrhosis Patients Recruiting

The Impact of Low-Dose Esketamine Combined With Ciprofol on the Quality of Early Postoperative Recovery Among Elderly Patients Undergoing Painless Gastroscopy Active, not recruiting

Efficacy of Apixaban in the Treatment of Portal Vein Thrombosis Occurring More Than One Year After LS Recruiting

Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection Recruiting

Other trials for the same condition

Ambispective Cohort Study of Precision Medicine for Primary Hepatobiliary Cancer Based on Next-generation Sequencing Recruiting

Adjuvant Stereotactic Body Radiotherapy (SBRT) for Hepatocellular Carcinoma After Hepatectomy With Narrow Margin: a Prospective, Multi-center, Randomized Controlled, Open-labelled, Phase III Study Starting soon

Perioperative Sintilimab Plus Bevacizumab Biosimilar and TACE-HAIC for HCC Patients With PVTT: A Phase-2 Clinical Trial Recruiting

HAIC vs. TACE Combined With Sintilimab and Bevacizumab for Intermediate HCC (Beyond Up-To-Seven) Recruiting

Anlotinib Hydrochloride Capsules Combined With Penpulimab Injection for the Treatment of Hepatocellular Carcinoma at High Risk of Recurrence. Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05433467 on ClinicalTrials.gov ↗ ← All trials in China