LSG: Laparoscopic sleeve gastrectomy (LSG) together with medical treatment aiming the control of cardiovascular risks including hypertension, diabetes mellitus or dyslipidemia.
RYGB: Roux-en-Y gastric bypass (LRYGB) together with medical treatment aiming the control of cardiovascular risks including hypertension, diabetes mellitus or dyslipidemia.
Study summary
The purpose of this study is to investigate the effect of bariatric surgery on cardiac function assessed by echocardiography in patients with hypertension.
Eligibility
Sex
ALL
Min age
17 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria:
* 18-70 years old
* BMI\>24kg/m2
* Bariatric surgery patients of Beijing Friendship Hospital
* History of hypertension and treated with ≥2 antihypertensive drugs for more than 4 weeks
* No major barriers to provide written consent
Exclusion Criteria:
* Secondary hypertension, except because of sleep apnea
* cardiovascular disease (myocardial infarction, heart failure, stroke or coronary revascularization) within 6 months
* Severe concomitant diseases (autoimmune disease, malignancy, late stage of liver diseases, respiratory diseases and digestive diseases)
* Unable to understand or comply with the study procedures
Primary outcome measure(s)
Changes on left ventricular ejection fraction (LVEF) — 12 months Changes on LVEF in % assessed with the use of transthoracic echocardiography (TTE).
Trial sites (1)
Facility
City
Region
Status
Beijing Friendship Hospital, Capital Medical University
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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