Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) Study

NCT03233087 · tracked via the Priya Life Science China tracker

Sponsor

Beijing Institute of Heart, Lung and Blood Vessel Diseases

Phase

Observational

Started

2014-03-01

Last updated

2024-06-27

Condition(s) studied

Aortic AneurysmAortic Dissection

Study summary

The registry study aims to determine serial biomarkers to diagnosis and prognosis of aortic aneurysm/aortic dissection.

Eligibility

Sex

ALL

Min age

18 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: Retrospective * All patients who were referred to the surgical service for evaluation and management of aortic dissection were included. Perspective * Patients with initial suspicion of having AAD were perspectively enrolled. Exclusion Criteria: Retrospective * Patients who received packed red blood cells, whole blood, or platelets less than 10 days before the blood sample was taken; * Patients with aortic trauma, pseudo aneurysm, history of heart failure, renal dysfunction, severe pulmonary diseases, or active cancer; * Patients who entered the hospital for checkups after surgery. Perspective * Patients in whom there is little or no suspicion of a life-threatening disease; * Patients with confirmed acute myocardial infarction,angina or pulmonary embolism * The symptoms were clearly not related to AD (e.g. pleurisy, pneumonia, acute abdominal diseases).

Primary outcome measure(s)

Dignosis of each participant — These data is collected from the cases' medical record in an average of 6 month after the sample recruiting
1. Patients with Aneurysm/Dissection had image information from ultrasound cardiograms and computed tomography to confirm the final diagnosis. 2. AMI if they had chest pain lasting \>20 min, diagnostic serial ECG changes comprising new pathological Q waves or ST-segment and T-wave changes, and a plasma creatine kinase-MB elevation greater than twice the normal level or cardiac troponin I (cTnI) level greater than 0.1 ng/mL. 3. Diagnosis of PE was confirmed by positive spiral computed tomography or pulmonary angiography, a high probability on ventilation perfusion scintigraphy, or a proximal deep vein thrombosis documented on compression ultrasonography or angiography.
Prognosis of each participant — These data is collected from the cases' medical record or during follow-up visit at 2-4 years after discharge.
Prognosis information including all-cause mortality and in-hospital mortality.

Trial sites (1)

Facility	City	Region	Status
Beijing Anzhen Hospital	Beijing	Beijing Municipality	Recruiting

More Beijing Institute of Heart, Lung and Blood Vessel Diseases trials in China

A Registry Study of Biomarkers in Heart Valve Disease Recruiting

A Registry Study on Biomarkers of Takayasu's Arteritis (ARSBTA) Recruiting

Other trials for the same condition

Guo&Amp;'s Distal Entry Tear Repair With WeFlow-EndoPatch System (Gallant Study) Recruiting

Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics Recruiting

Protective Effect of Ulinastatin and Thymosin α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA XI) Enrolling by invitation

PregnAncy-Related Aortic DISsEction in China Recruiting

Study Comparing Hemiarch Replacement and Hemiarch Plus Stent Implantation in Acute Aortic Dissection Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03233087 on ClinicalTrials.gov ↗ ← All trials in China