Pregnancy ComplicationAortic DissectionMarfan SyndromeLoeys-Dietz SyndromeVascular Ehlers-Danlos SyndromeMaternal and Neonatal Outcomes
Investigational drug(s) / intervention(s)
Intervention strategies including medication or surgery
Intervention strategies including medication or surgery: Medication or surgery (delivery or surgery first, or single-stage delivery and surgery) is determined based on gestational age and the type of AD, and also in consideration of the decisions made by the patient and their relatives.
Study summary
A multicenter observational study on pregnancy-related aortic dissection
Eligibility
Sex
FEMALE
Min age
16 Years
Max age
55 Years
Healthy volunteers
No
Inclusion Criteria:
* Aortic dissection is diagnosed based on symptoms and physical findings, and confirmed by computed tomographic angiography (CTA) and/or transthoracic echocardiography
* Aortic dissection occurring during pregnancy or within 12 weeks postpartum
Exclusion Criteria:
* Previous history of aortic dissection, but no new aortic dissection occurring during pregnancy or within 12 weeks postpartum
Primary outcome measure(s)
Early-term mortality of mothers and fetuses (or newborns) — Death within 30 days after treatment. All-cause mortality within 30 days after treatment.
Long-term mortality of mothers and children — Through study completion, an average of 3 years. All-cause mortality during the follow-up period.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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