Microvascular Monitoring in Circulatory Shock and Sepsis (MiMICSS)

NCT05985525 · tracked via the Priya Life Science Canada tracker

Sponsor

University of Manitoba

Phase

Observational

Started

2022-05-27

Last updated

2025-08-24

Condition(s) studied

SepsisShockCritical Illness

Investigational drug(s) / intervention(s)

Skeletal muscle and cerebral NIRS (research device)

Skeletal muscle and cerebral NIRS (research device): NIRS applied on skeletal muscle and brain on days 1, 3, and 8 of ICU admission. Monitoring applied for up to 24hrs on each day.

Study summary

Investigation of the feasibility of using near-infrared spectroscopy (NIRS) to monitor microvascular function in critically ill patients.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Admitted to ICU * Receiving invasive mechanical ventilation Exclusion Criteria: * Body Mass Index \>40 * More than 24 hours has elapsed since ICU admission * Death is deemed to be imminent and inevitable during the next 24 hours * Known allergy to the textile components of the device * Significant clinical jaundice, ecchymosis * COVID positive microbiological result * The treating clinician believes that participation in the domain would not be in the best interests of the patient * Consent declined from patient or authorized third party

Primary outcome measure(s)

Recruitment — 30 days
Recruitment of two patients per month from each study site

Trial sites (1)

Facility	City	Region	Status
Health Sciences Centre Winnipeg	Winnipeg	Manitoba	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05985525 on ClinicalTrials.gov ↗ ← All trials in Canada