A New Ultrasonographic Tool to Assess Pulmonary Strain in the ICU

NCT03405779 · tracked via the Priya Life Science Canada tracker

Sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

Phase

Observational

Started

2018-03-12

Last updated

2025-09-18

Condition(s) studied

Mechanical Ventilation ComplicationVentilator-Induced Lung Injury

Investigational drug(s) / intervention(s)

Lung ultrasonography

Lung ultrasonography: Mechanically ventilated patients suffering from pulmonary diseases will undergo a lung ultrasonography during their stay in the intensive care unit (ICU)

Study summary

The primary objective of the study is to create a small dataset of regional pulmonary strain values in patients suffering from pulmonary diseases under mechanical ventilation in an intensive care setting.

Hypothesis: The analysis of lung ultrasonographic sequences using speckle-tracking allows the determination of local pleural strain in 4 predetermined pulmonary areas in mechanically ventilated patients suffering from pulmonary diseases.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Adult intensive care patients under mechanical ventilation suffering from a pulmonary disease with a static lung compliance of less than 40 mL/cm H2O. Exclusion Criteria: * Obesity (Body Mass Index superior to 30 kg/m2) * Previous thoracic procedure (chest tube, thoracotomy, thoracoscopy) * Intra-abdominal pressure inferior to 15 mm Hg (if available) * Previous participation to the study

Primary outcome measure(s)

Average absolute lateral deformation — At the end of study on Day 1
Change in percentage from baseline expiratory value

Trial sites (1)

Facility	City	Region	Status
Centre Hospitalier de l'Université de Montréal (CHUM)	Montreal	Quebec	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03405779 on ClinicalTrials.gov ↗ ← All trials in Canada