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Clinical Trials in Canada / NCT01747304
Active, not recruiting Observational

Evaluation of IVA (SE Femur Scans) to Identify Incomplete AFFs

NCT01747304 · tracked via the Priya Life Science Canada tracker
Phase
Observational
Started
2012-07
Last updated
2025-08-19

Condition(s) studied

Atypical Femur Fracture

Investigational drug(s) / intervention(s)

DXA Se femur scans (previously called IVA femur)

DXA Se femur scans (previously called IVA femur): Single Energy Beam (previously called inter-vertebral assessment) by Dual energy x-ray absorptiometry of affected femur

Study summary

DXA scanners are routinely used to assess bone mineral density (BMD) and fracture risk in osteoporosis patients. They provide detailed bone imaging in a low radiation setting. Hologic manufactures scanners that are able to perform high definition instant vertebral fracture assessment (HD-IVA) used to screen at-risk patients for asymptomatic spine fractures instantly and reliably at the same time they are having their yearly BMD. We wish to investigate whether this same proven technology (HD-IVA scan mode) used on femurs (the scan mode is now called SE Femur scans) can be used to screen for atypical fractures of the femur in patients at risk for these debilitating fractures. In this proof of concept study, we propose to examine whether DXA scanners can provide a sensitive low radiation screening method to identify incomplete AFFs in patients with known incomplete AFFs and in patients at risk.

Eligibility

Sex
FEMALE
Min age
18 Years
Max age
100 Years
Healthy volunteers
Accepted
Inclusion Criteria: Known AFF group 1. A subject must have experienced an incomplete atypical low trauma fracture of the femoral shaft; 2. Is a patient at the UHN osteoporosis clinic. Comparison Group 1. Must be scheduled for a bone mineral density scan at UHN 2. Have been on any bisphosphonate for 5 years or longer, and; 3. Have unexplained symptoms of leg, hip, thigh, or knee pain. Exclusion Criteria: * There are no exclusions

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
University Health Network Toronto Ontario

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Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT01747304 on ClinicalTrials.gov ↗ ← All trials in Canada