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Xencor clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine and the EU Clinical Trials Information System (CTIS) — current trials in our USA, UK and EU (CTIS) registers with Xencor as lead sponsor. Synced 26 Sep 2026
6Current trials
4Recruiting now
1Drug in these trials
3Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Xencor is the lead sponsor of 6 current clinical trials in our USA, UK and EU (CTIS) registers. 4 are recruiting patients now. The most common phase is Phase 1. The drugs named most often in its trials are XmAb541. The most-studied condition is Ovarian Cancer.

ClinicalTrials.gov trials by status

  • Recruiting480%
  • Active, closed120%

Trials by phase

  • Phase 1360%
  • Phase 1/2120%
  • Phase 2120%
01

Clinical trials sponsored by Xencor

5 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma
NCT05433142 · ClinicalTrials.gov ↗ · Clear Cell Renal Cell Carcinoma
Phase 1 Recruiting 2022-06 UK, USA
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
NCT06619990 · ClinicalTrials.gov ↗ · Ulcerative Colitis (UC)
Phase 1/2 Recruiting 2024-10 USA
Phase 1, Safety and Tolerability Study of XmAb541 and XmAb808 in Advanced Solid Tumors
NCT07593092 · ClinicalTrials.gov ↗ · Ovarian Cancer
Drug: XmAb541
Phase 1 Recruiting 2026-06 USA
Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors
NCT06276491 · ClinicalTrials.gov ↗ · Ovarian Cancer, Endometrial Cancer, Germ Cell Tumor
Drug: XmAb541
Phase 1 Recruiting 2024-04 USA
A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies
NCT05032040 · ClinicalTrials.gov ↗ · Ovarian Cancer, Clear Cell Carcinoma, Endometrial Cancer
Phase 2 Active, closed 2022-07 USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Xencor in the EU trials register (CTIS)

1 trial

Authorised or ongoing trials in the EU Clinical Trials Information System with Xencor as sponsor. Some are the same study as a ClinicalTrials.gov record above; the two registries share no common ID. Trials with a site in Ireland are listed first.

StudyPhaseStatusCountries
A Study Testing the Investigational Drug XmAb541 in people with Advanced Cancer
2025-521981-90-00 · CTIS ↗ · Neoplasms
Phase 1 Ongoing Spain, France, Belgium + 1 more
03

Drugs in Xencor trials

1 compound

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

04

Conditions in Xencor trials

8 conditions
Ovarian Cancer3Endometrial Cancer2Clear Cell Renal Cell Carcinoma1Ulcerative Colitis (UC)1Germ Cell Tumor1Testicular Germ Cell Tumor1Clear Cell Carcinoma1Cervical Carcinoma1
05

By trial register

RegisterTrialsRecruiting
Clinical trials in USA54
Clinical trials in UK11
EU register (CTIS)1—

A trial with sites in more than one country appears in each of those registers.

06

Other sponsors in Ovarian Cancer

SponsorTrials
Tongji Hospital7
Anhui Provincial Cancer Hospital3
Hangzhou SynRx Therapeutics Biomedical Technology3
Genmab2
Tubulis2
USWM CT2
BeiGene2
Imunon2
CanariaBio2
Chongqing University Cancer Hospital2

Sponsors with the most current trials registered for this condition.

07

Questions about Xencor trials

How many clinical trials does Xencor sponsor?

Xencor is the lead sponsor of 5 current trials on ClinicalTrials.gov in our USA and UK registers, and 1 authorised or ongoing trial in the EU register (CTIS), as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Xencor trials recruiting?

Yes. 4 of its 5 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Xencor testing?

Its current trials name 1 drug or biological as interventions. The most frequent are XmAb541 (2). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.