Wave Life Sciences USA is the lead sponsor of 4 current clinical trials in our UK and USA registers. 2 are recruiting patients now. The most common phase is Phase 1/2. The drugs named most often in its trials are WVE-N531. The most-studied condition is Duchenne Muscular Dystrophy.
| Study | Phase | Status | Start | Registers |
|---|---|---|---|---|
|
Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)
NCT04906460 · ClinicalTrials.gov ↗ · Duchenne Muscular Dystrophy
Drug: WVE-N531 |
Phase 1/2 | Recruiting | 2021-09 | UK, USA |
|
A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity
NCT06842186 · ClinicalTrials.gov ↗ · Overweight and Obesity
|
Phase 1/2 | Recruiting | 2025-01 | UK, USA |
|
Open-Label Extension Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy
NCT07209332 · ClinicalTrials.gov ↗ · Duchenne Muscular Dystrophy
Drug: WVE-N531 |
Phase 2 | By invitation | 2025-12 | UK |
|
A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD
NCT06405633 · ClinicalTrials.gov ↗ · Alpha-1 Antitrypsin Deficiency
|
Phase 1/2 | Active, closed | 2024-07 | UK |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.
Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in UK | 4 | 2 |
| Clinical trials in USA | 2 | 2 |
A trial with sites in more than one country appears in each of those registers.
| Sponsor | Trials |
|---|---|
| Sarepta Therapeutics | 6 |
| Italfarmaco | 3 |
| Solid Biosciences | 3 |
| NS Pharma | 3 |
| REGENXBIO | 3 |
| Edgewise Therapeutics | 2 |
Sponsors with the most current trials registered for this condition.
Wave Life Sciences USA is the lead sponsor of 4 current trials on ClinicalTrials.gov in our UK and USA registers, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.
Yes. 2 of its 4 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Its current trials name 1 drug or biological as interventions. The most frequent are WVE-N531 (2). The number in brackets is how many of its trials name each drug.
Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.
Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.