Kartos Therapeutics is the lead sponsor of 4 current clinical trials in our USA and UK registers. 3 are recruiting patients now. The most common phase is Phase 1/2. The drugs named most often in its trials are KRT-232, Navtemadlin and Ruxolitinib. The most-studied condition is Diffuse Large B Cell Lymphoma.
| Study | Phase | Status | Start | Registers |
|---|---|---|---|---|
|
Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL
NCT04502394 · Diffuse Large B Cell Lymphoma, Chronic Lymphocytic Leukemia, Non Hodgkin Lymphoma
Drugs: Acalabrutinib, KRT-232 |
Phase 1/2 | Recruiting | 2021-02 | UK, USA |
|
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
NCT06479135 · ClinicalTrials.gov ↗ · Myelofibrosis, Post-PV MF, Post-ET Myelofibrosis
Drugs: Navtemadlin, Ruxolitinib |
Phase 3 | Recruiting | 2024-06 | UK, USA |
|
Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer
NCT05797831 · ClinicalTrials.gov ↗ · Endometrial Cancer
Drug: Navtemadlin |
Phase 2/3 | Recruiting | 2023-07 | USA |
|
KRT-232 Compared to Ruxolitinib in Patients With Phlebotomy-Dependent Polycythemia Vera
NCT03669965 · ClinicalTrials.gov ↗ · Polycythemia Vera
Drugs: KRT-232, Ruxolitinib |
Phase 2 | Active, closed | 2019-01 | USA |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.
Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 4 | 3 |
| Clinical trials in UK | 2 | 2 |
A trial with sites in more than one country appears in each of those registers.
| Sponsor | Trials |
|---|---|
| Jiangsu Topcel-KH Pharmaceutical | 1 |
Sponsors with the most current trials registered for this condition.
Kartos Therapeutics is the lead sponsor of 4 current trials on ClinicalTrials.gov in our USA and UK registers, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.
Yes. 3 of its 4 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Its current trials name 4 drugs and biologicals as interventions. The most frequent are KRT-232 (2), Navtemadlin (2), Ruxolitinib (2) and Acalabrutinib (1). The number in brackets is how many of its trials name each drug.
Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.
Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.