Source: ClinicalTrials.gov, U.S. National Library of Medicine and the EU Clinical Trials Information System (CTIS) — current trials in our USA, UK, Ireland, India, China and EU (CTIS) registers with Ionis Pharmaceuticals as lead sponsor.Synced 26 Sep 2026
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Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance
Ionis Pharmaceuticals is the lead sponsor of 20 current clinical trials
in our USA, UK, Ireland, India, China and EU (CTIS) registers.
9 are recruiting patients now. The most common phase is Phase 3. The drugs named most often in its trials are Olezarsen, Donidalorsen and Eplontersen. The most-studied condition is Familial Chylomicronemia Syndrome.
ClinicalTrials.gov trials by status
Recruiting947%
Active, closed947%
By invitation15%
Trials by phase
Phase 31158%
Phase 1/2421%
Phase 1211%
Observational15%
Phase 215%
01
Clinical trials sponsored by Ionis Pharmaceuticals
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.
02
Ionis Pharmaceuticals in the EU trials register (CTIS)
1 trial
Authorised or ongoing trials in the EU Clinical Trials Information System with Ionis Pharmaceuticals as sponsor. Some are the same study as a ClinicalTrials.gov record above; the two registries share no common ID. Trials with a site in Ireland are listed first.
Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.
A trial with sites in more than one country appears in each of those registers.
06
Questions about Ionis Pharmaceuticals trials
How many clinical trials does Ionis Pharmaceuticals sponsor?
Ionis Pharmaceuticals is the lead sponsor of 19 current trials on ClinicalTrials.gov in our USA, UK, Ireland, India and China registers, and 1 authorised or ongoing trial in the EU register (CTIS), as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.
Are Ionis Pharmaceuticals trials recruiting?
Yes. 9 of its 19 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Which drugs is Ionis Pharmaceuticals testing?
Its current trials name 4 drugs and biologicals as interventions. The most frequent are Olezarsen (4), Donidalorsen (2), Eplontersen (2) and Obudanersen (2). The number in brackets is how many of its trials name each drug.
Does Ionis Pharmaceuticals have clinical trials in Ireland?
Yes. 1 trial in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.
Where does this information come from?
Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.
How this page is built
Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.
Please verify before you rely on this.
This page is general information for life-science and pharmaceutical professionals. It is
not medical advice, and it has not been reviewed by a clinician — our editorial
team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most
recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC)
and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not
automatically interchangeable, and approvals, brand names and indications differ between the US, the
EU/Ireland (EMA/HPRA) and other regions.
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