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Deciphera Pharmaceuticals clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine and the EU Clinical Trials Information System (CTIS) — current trials in our USA, UK, China and EU (CTIS) registers with Deciphera Pharmaceuticals as lead sponsor. Synced 26 Sep 2026
13Current trials
7Recruiting now
6Drugs in these trials
4Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Deciphera Pharmaceuticals is the lead sponsor of 13 current clinical trials in our USA, UK, China and EU (CTIS) registers. 7 are recruiting patients now. The most common phase is Phase 3. The drugs named most often in its trials are Vimseltinib, Ripretinib and Sunitinib. The most-studied condition is Tenosynovial Giant Cell Tumor.

ClinicalTrials.gov trials by status

  • Recruiting764%
  • Active, closed436%

Trials by phase

  • Phase 3327%
  • Phase 1/2327%
  • Phase 1327%
  • Phase 219%
  • Observational19%
01

Clinical trials sponsored by Deciphera Pharmaceuticals

11 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)
NCT06619561 · Chronic Graft-Versus-Host Disease (cGVHD)
Phase 2 Recruiting 2024-11 USA
Evaluate the Effect of Vimseltinib on Pharmacokinetics of Combined Oral Contraceptive (Ethinyl Estradiol/Levonorgestrel)
NCT07539090 · ClinicalTrials.gov ↗ · Healthy Participants
Phase 1 Recruiting 2026-06 USA
Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp) Inhibition in Healthy Male Participants
NCT07744802 · ClinicalTrials.gov ↗ · Healthy Male Participants
Phase 1 Recruiting 2026-09 USA
A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies
NCT05957367 · ClinicalTrials.gov ↗ · GIST
Phase 1/2 Recruiting 2023-09 USA
A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)
NCT06630234 · ClinicalTrials.gov ↗ · Gastrointestinal Stromal Tumor (GIST)
Phase 1/2 Recruiting 2024-12 USA
Study of DCC-2812 in Participants With Advanced Genitourinary Cancers
NCT06966024 · ClinicalTrials.gov ↗ · Renal Cell Carcinoma, Urothelial Carcinoma, Castration-resistant Prostate Cancer
Phase 1 Recruiting 2025-08 USA
MOVE: Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With Vimseltinib
NCT07075471 · ClinicalTrials.gov ↗ · Tenosynovial Giant Cell Tumor
Observational Recruiting 2025-09 USA
Study of Vimseltinib for Tenosynovial Giant Cell Tumor
NCT05059262 · Tenosynovial Giant Cell Tumor, Pigmented Villonodular Synovitis, Giant Cell Tumor of Tendon Sheath
Phase 3 Active, closed 2021-10 UK, USA
A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib
NCT03673501 · ClinicalTrials.gov ↗ · Gastrointestinal Stromal Tumors
Phase 3 Active, closed 2019-02 UK, USA, China
A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib
NCT05734105 · ClinicalTrials.gov ↗ · GIST
Phase 3 Active, closed 2023-12 UK, USA, China
Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor
NCT03069469 · ClinicalTrials.gov ↗ · Advanced Malignant Neoplasm, Pigmented Villonodular Synovitis, Giant Cell Tumor of Tendon Sheath
Phase 1/2 Active, closed 2017-02 UK, USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Deciphera Pharmaceuticals in the EU trials register (CTIS)

2 trials

Authorised or ongoing trials in the EU Clinical Trials Information System with Deciphera Pharmaceuticals as sponsor. Some are the same study as a ClinicalTrials.gov record above; the two registries share no common ID. Trials with a site in Ireland are listed first.

StudyPhaseStatusCountries
A Phase 3 Randomized, Double-blind, Placebo-controlled Global Study of Sapablursen in Polycythemia Vera
2025-524669-25-00 · Hemic and Lymphatic Diseases
Phase 3 Authorised Austria, Czechia, Italy + 6 more
A Phase 3, Multi-regional, Open-label, Randomized Study of Tirabrutinib vs Rituximab and Temozolomide in Participants with Relapsed/Refractory Primary Central Nervous System Lymphoma
2025-523389-26-00 · CTIS ↗ · Nervous System Diseases
Phase 3 Ongoing Czechia, Germany, Italy + 6 more
03

Drugs in Deciphera Pharmaceuticals trials

6 compounds

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

04

Conditions in Deciphera Pharmaceuticals trials

14 conditions
Tenosynovial Giant Cell Tumor3Pigmented Villonodular Synovitis2Giant Cell Tumor of Tendon Sheath2GIST2Tenosynovial Giant Cell Tumor, Diffuse1Gastrointestinal Stromal Tumors1Advanced Malignant Neoplasm1Chronic Graft-Versus-Host Disease (cGVHD)1Healthy Participants1Healthy Male Participants1Gastrointestinal Stromal Tumor (GIST)1Renal Cell Carcinoma1Urothelial Carcinoma1Castration-resistant Prostate Cancer1
05

By trial register

RegisterTrialsRecruiting
Clinical trials in USA117
Clinical trials in UK40
Clinical trials in China20
EU register (CTIS)2—

A trial with sites in more than one country appears in each of those registers.

06

Other sponsors in Tenosynovial Giant Cell Tumor

SponsorTrials
Abbisko Therapeutics2

Sponsors with the most current trials registered for this condition.

07

Questions about Deciphera Pharmaceuticals trials

How many clinical trials does Deciphera Pharmaceuticals sponsor?

Deciphera Pharmaceuticals is the lead sponsor of 11 current trials on ClinicalTrials.gov in our USA, UK and China registers, and 2 authorised or ongoing trials in the EU register (CTIS), as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Deciphera Pharmaceuticals trials recruiting?

Yes. 7 of its 11 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Deciphera Pharmaceuticals testing?

Its current trials name 6 drugs and biologicals as interventions. The most frequent are Vimseltinib (4), Ripretinib (2), Sunitinib (2), Rituximab (1) and Temozolomide (1). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.